Institutional Repository UDD

Artículos Medicina y Ciencias de la Salud

Artículos Medicina y Ciencias de la Salud

 

Recent Submissions

  • Israel, Yedy; Quintanilla, María Elena; Ezquer, Fernando; Morales, Paola; Santapau, Daniela; Berríos-Cárcamo, Pablo; Ezquer, Marcelo; Olivares, Belen; Herrera-Marschitz, Mario (2020)
    Chronic alcohol intake leads to neuroinflammation and cell injury, proposed to result in alterations that perpetuate alcohol intake and cued-relapse. Studies show that brain oxidative stress is consistently associated with ...
  • Ezquer, Fernando; Quintanilla, María Elena; Morales, Paola; Santapau, Daniela; Ezquer, Marcelo; Kogan, Marcelo J.; Salas-Huenuleo, Edison; Herrera-Marschitz, Mario; Israel, Yedy (2020)
    Chronic ethanol consumption leads to brain oxidative stress and neuroinflammation, conditions known to potentiate and perpetuate each other. Several studies have shown that neuroinflammation results in increases in chronic ...
  • Israel, Yedy; Quintanilla, María Elena; Ezquer, Fernando; Morales, Paola; Rivera-Meza, Mario; Karahanian, Eduardo; Ezquer, Marcelo; Herrera-Marschitz, Mario (2020)
    Studies reviewed show that lentiviral gene therapy directed either at inhibiting the synthesis of brain acetaldehyde generated from ethanol or at degrading brain acetaldehyde fully prevent ethanol intake by rats bred for ...
  • Quintanilla, María Elena; Ezquer, Fernando; Morales, Paola; Santapau, Daniela; Berríos-Cárcamo, Pablo; Ezquer, Marcelo; Herrera-Marschitz, Mario; Israel, Yedy (2019)
    Background: Chronic consumption of most drugs of abuse leads to brain oxidative stress and neuroinflammation, which inhibit the glutamate transporter GLT-1, proposed to perpetuate drug intake. The present study aimed at ...
  • Atanasova, Velina S.; Pourreyron, Celine; Farshchian, Mehdi; Christian A., Brown IV; Watt, Stephen A.; Wright, Sheila; Warkala, Michael; Guttmann-Gruber, Christina; Piñón Hofbauer, Josefina; Fuentes, Ignacia; Prisco, Marco; Rashidghamat, Elham; Has, Cristina; Palisson, Francis; Hovnanian, Alain; McGrath, John A.; Mellerio, Jemima E.; Bauer, Johann; South, Andrew P. (2019)
    Purpose: Squamous cell carcinoma (SCC) of the skin is the leading cause of death in patients with the severe generalized form of the genetic disease recessive dystrophic epidermolysis bullosa (RDEB). Although emerging data ...
  • Ribeiro E., Grazielle; Luis Edgardo, Leon; Perez, Ruth; Cuiza V., Analia; Vial, Pablo; Ferres, Marcela; Mertz, Gregory J.; Vial, Cecilia (2019)
    Andes orthohantavirus (ANDV) is an important human pathogen causing hantavirus cardiopulmonary syndrome (HCPS) with a fatality rate of 30% in Chile. Around 60% of all cases have a severe clinical course, while the others ...
  • Martínez-Valdebenito, Constanza; Angulo, Jenniffer; Corre, Nicole Le; Marco, Claudia; Vial, Cecilia; Miquel, Juan Francisco; Cerda, Jaime; Mertz, Gregory; Vial, Pablo; Lopez-Lastra, Marcelo; Ferrés, Marcela (2019)
    The Andes Orthohantavirus (ANDV), which causes the hantavirus cardiopulmonary syndrome, enters cells via integrins, and a change from leucine to proline at residue 33 in the PSI domain (L33P), impairs ANDV recognition. ...
  • Hoste, Esther; Maueröder, Christian; Hove, Lisette van; Catrysse, Leen; Vikkula, Hanna-Kaiza; Sze, Mozes; Maes, Bastiaan; Karjosukarso, Dyah; Martens, Liesbet; Goncalves, Amanda; Parthoens, Eef; Roelandt, Ria; Declercq, Wim; Fuentes, Ignacia; Palisson, Francis; Gonzalez, Sergio; Salas-Alanis, Julio C.; Boon, Louis; Huebener, Peter; Mulder, Klaas Willem; Ravichandran, Kodi; Saeys, Yvan; Schwabe, Robert Felix; Loo, Geert van (2019)
    Regenerative responses predispose tissues to tumor formation by largely unknown mechanisms. High-mobility group box 1 (HMGB1) is a dangerassociated molecular pattern contributing to inflammatory pathologies. We show that ...
  • Lalor, Leah; Titeux, Matthias; Palisson, Francis; Fuentes, Ignacia; Yubero, María; Tasanen, Kaisa; Huilaja, Laura; Has, Cristina; Tadini, Gianluca; Haggstrom, Anita N.; Hovnanian, Alain; Lucky, Anne W. (2019)
    Background/Objectives: Epidermolysis bullosa is a group of diseases caused by mutations in skin structural proteins. Availability of genetic sequencing makes identification of causative mutations easier, and genotype‐phenotype ...
  • Schwieger-Briel, A.; Fuentes, Ignacia; Castiglia, D.; Barbato, A.; Greutmann, M.; Leppert, J.; Duchatelet, S.; Hovnanian, A.; Burattini, S.; Yubero, María; Ibañez-Arenas, Rodrigo; Rebolledo-Jaramillo, B.; Gräni, C.; Ott, H.; Theiler, M.; Weibel, L.; Paller, A.S.; Zambruno, G.; Fischer, J.; Palisson, Francis; Has, C. (2019)
    Inherited epidermolysis bullosa (EB) comprises rare heterogeneous disorders characterized by cutaneous and mucosal fragility. Most of the 20 proteins affected have structural functions. Recently, a previously undescribed ...
  • Rencoret, Guillermo; Vivanco, Marcelo; Castillo, Felipe; Schiappacasse, Giancarlo; de Aretxabala, Xabier; Bianchi, Víctor; Hepp, Juan; Ríos, Horacio (2019)
    Introduction: Intrahepatic cholangiocarcinoma is the second most common primary liver tumor and surgical resection the only valid curative treatment. Case reports: We describe two patients harboring an intrahepatic ...
  • Wagner, Pablo; Wagner, Emilio; López, M.; Etchevers, G.; Valencia, O.; Guzmán-Venegas, R. (2019)
    Background: Different techniques have been described for percutaneous Achilles tendon rupture repair, but no biomechanical evaluation has been performed separately for proximal and distal suturing techniques. The purpose ...
  • Has, Cristina; Liu, Lu; Bolling, Marieke; Charlesworth, Alexandra V.; Hachem, May El; Escámez, María José; Fuentes, Ignacia; Büche, Sarah; Hiremagalore, Ravi; Pohla-Gubo, Gabriele; Akker, Peter van den; Wertheim-Tysarowska, Katarzyna; Zambruno, Giovanna (2019)
    The overall objective of this guideline is to provide the user with information on the laboratory diagnosis of inherited epidermolysis bullosa (EB) to improve outcomes (Table 1). An accurate diagnosis and subclassification ...
  • Wagner, Pablo; Wagner, Emilio; Ortiz, C.; Zanolli, Diego; Keller, A.; Maffulli, N. (2019)
    Background: To report the mid-term clinical results of endoscopic assisted surgery for patients suffering from chronic recalcitrant painful mid-portion Achilles tendinopathy who failed conservative management for at least ...
  • Díaz-Torrente, Ximena; Quintiliano-Scarpelli, Daiana (2019)
    Breakfast is one of the most important meals of the day. A good quality breakfast must include dairy products, cereals, and fruits. The aim of this study is to determine breakfast dietary patterns and their nutritional ...
  • Vial, Cecilia; Valdivieso, Francisca; Cuiza V., Analía; Delgado B., Iris; Ribeiro E., Grazielle; Llop R., Elena; Ferrés G., Marcela; Repetto, Gabriela; Riquelme O., Raúl; Rioseco Z., M. Luisa; Calvo A., Mario; Mertz, Gregory; Vial, Pablo (2019)
    Background: Hantavirus cardiopulmonary syndrome (HCPS) is caused by new world hantaviruses, among which Andes hantavirus (ANDV) is endemic to Chile and Southern Argentina. The disease caused by ANDV produces plasma leakage ...
  • Rosenberger, Leonie; Ezquer, Marcelo; Lillo-Vera, Fernando; Pedraza, Paulina L.; Ortúzar, María Ignacia; González, Paz L.; Figueroa-Valdés, Aliosha I.; Cuenca, Jimena; Ezquer, Fernando; Khoury, Maroun; Alcayaga-Miranda, Francisca (2019)
    Recently, exosomes secreted by menstrual mesenchymal stem cells have been identified as inhibitory agents of tumor angiogenesis and modulators of the tumor cell secretome in prostate and breast cancer. However, their direct ...
  • Weitzel, Thomas; Martínez-Valdebenito, Constanza; Acosta-Jamett, Gerardo; Jiang, Ju; Richards, Allen; Abarca, Katia (National Center for Infectious Diseases, 2019)
    Endemic scrub typhus was recently detected on Chiloé Island in southern Chile. We report a series of cases, acquired over a wide geographical range in continental Chile during 2016-2018, demonstrating that this emerging ...
  • Lobos-González, Lorena; Bustos, Rocío; Campos, América; Silva, Valeria; Silva, Verónica; Jeldes, Emanuel; Salomon, Carlos; Varas-Godoy, Manuel; Cáceres-Verschae, Albano; Durán, Eduardo; Vera, Tamara; Ezquer, Fernando; Ezquer, Marcelo; Burzio, Verónica; Villegas, Jaime (Nature Publishing Group, 2020)
    During intercellular communication, cells release extracellular vesicles such as exosomes, which contain proteins, ncRNAs and mRNAs that can influence proliferation and/or trigger apoptosis in recipient cells, and have ...
  • Arce, Maximiliano; Pinto, Mauricio; Galleguillos, Macarena; Muñoz, Catalina; Lange, Soledad; Ramirez, Carolina; Erices, Rafaela; González, Pamela; Velásquez, Ethel; Tempio, Fabián; López, Mercedes; Salazar-Onfray, Flavio; Cautivo, Kelly; Kalergis, Alexis; Cruz, Sebastián; Lorena Lobos-González, Lorena Lobos-González; Lladser, Álvaro; Lobos-González, Lorena; Valenzuela, Guillermo; Olivares, Nixa; Sáez, Claudia; Koning, Tania; Sánchez, Fabiola; Fuenzalida, Patricia; Godoy, Alejandro; Contreras, Pamela; Leyton, Lisette; Lugano, Roberta; Dimberg, Anna; Quest, Andrew; Owen, Gareth (Multidisciplinary Digital Publishing Institute (MDPI), 2019)
    Hypercoagulable state is linked to cancer progression; however, the precise role of the coagulation cascade is poorly described. Herein, we examined the contribution of a hypercoagulative state through the administration ...

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