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SKI regulates rRNA transcription and pericentromeric heterochromatin to ensure centromere integrity and genome stability

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Abstract

Accurate chromosome segregation and ribosomal gene expression silencing are essential for maintaining genome integrity, and disruptions in these processes are key for oncogenesis and cancer progressio...

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Pola-Véliz V, Carrero D, Sagredo EA, Inostroza V, Cappelli C, Rivas S, Bitrán M, Zambrano E, Gonzalez E, Morales F, Manterola M, Montecino M, Armisén R, Marcelain K. SKI regulates rRNA transcription and pericentromeric heterochromatin to ensure centromere integrity and genome stability. Neoplasia. 2025 Jul 2;67:101204. doi: 10.1016/j.neo.2025.101204

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