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Modeling Parkinson's Disease Heterogeneity to Accelerate Precision Medicine

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dc.contributor.author Olivares, Gonzalo
dc.contributor.author Olguín, Patricio
dc.contributor.author Klein, Andrés
dc.date.accessioned 2020-03-27T14:36:16Z
dc.date.available 2020-03-27T14:36:16Z
dc.date.issued 2019
dc.identifier.citation Trends Mol Med. 2019 Dec;25(12):1052-1055. doi: 10.1016/j.molmed.2019.09.004.
dc.identifier.uri http://hdl.handle.net/11447/3183
dc.identifier.uri https://doi.org/10.1016/j.molmed.2019.09.004
dc.description Centro de Genética y Genómica (ICIM)
dc.description.abstract mechanistic understanding of the diverse clinical manifestations of Parkinson's disease (PD) and variable patient response to treatments is lacking. Genetically diverse PD model organisms can be used to map modifier genes and understand clinically relevant phenotypes of varying severity. This strategy can accelerate the pace of discoveries for precision medicine purposes.
dc.language.iso en
dc.publisher Elsevier Ltd.
dc.subject Parkinson’s disease
dc.subject Customized therapies
dc.subject Genome-wide association studies
dc.subject Inbred animal organisms
dc.subject Modifier genes
dc.subject Precision medicine
dc.title Modeling Parkinson's Disease Heterogeneity to Accelerate Precision Medicine
dc.type Preprint


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