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Modeling Parkinson's Disease Heterogeneity to Accelerate Precision Medicine

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dc.contributor.author Olivares, Gonzalo
dc.contributor.author Olguín, Patricio
dc.contributor.author Klein, Andrés
dc.date.accessioned 2020-03-27T14:36:16Z
dc.date.available 2020-03-27T14:36:16Z
dc.date.issued 2019
dc.identifier.citation Trends Mol Med. 2019 Dec;25(12):1052-1055. doi: 10.1016/j.molmed.2019.09.004. es
dc.identifier.uri https://doi.org/10.1016/j.molmed.2019.09.004 es
dc.identifier.uri http://hdl.handle.net/11447/3183
dc.description Centro de Genética y Genómica (ICIM) es
dc.description.abstract mechanistic understanding of the diverse clinical manifestations of Parkinson's disease (PD) and variable patient response to treatments is lacking. Genetically diverse PD model organisms can be used to map modifier genes and understand clinically relevant phenotypes of varying severity. This strategy can accelerate the pace of discoveries for precision medicine purposes. es
dc.language.iso en es
dc.publisher Elsevier Ltd. es
dc.subject Parkinson’s disease es
dc.subject Customized therapies es
dc.subject Genome-wide association studies es
dc.subject Inbred animal organisms es
dc.subject Modifier genes es
dc.subject Precision medicine es
dc.title Modeling Parkinson's Disease Heterogeneity to Accelerate Precision Medicine es
dc.type Preprint es


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