Pharmacological treatment of bipolar depression

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dc.contributor.authorVázquez, Gustavo H.
dc.contributor.authorTondo, Leonardo
dc.contributor.authorUndurraga, Juan
dc.contributor.authorZaratiegui, Rodolfo
dc.contributor.authorSelle, Valerio
dc.contributor.authorBaldessarini, Ross J.
dc.date.accessioned2021-11-05T14:46:51Z
dc.date.available2021-11-05T14:46:51Z
dc.date.issued2014
dc.description.abstractBipolar depression remains a major challenge for psychiatric therapeutics. It is associated with disability and excess mortality, and accounts for three-quarters of the time spent in morbid states by treated patients with bipolar disorder. Major limitations of research on the treatment of depression in bipolar disorder include a paucity of short-term and lack of long-term trials, probably reflecting concern about inducing mania. In addition, polytherapy with multiple drugs appears to be widespread, but it is virtually untested for efficacy and safety. Here, we summarise the evidence concerning efficacy of treatment of bipolar depression with antidepressants, mood- stabilising anticonvulsants, lithium and second-generation antipsychotics.es
dc.identifier.citationAdvances in psychiatric treatment, 2014, 20: 193–201es
dc.identifier.urihttp://hdl.handle.net/11447/5030es
dc.identifier.urihttps://dx.doi.org/10.1192/apt.bp.113.011460
dc.language.isoenes
dc.subjectBipolar depressiones
dc.subjectPharmacological treatmentes
dc.subjectAntidepressantses
dc.subjectAnticonvulsantses
dc.subjectLithiumes
dc.subjectAntipsychoticses
dc.titlePharmacological treatment of bipolar depressiones
dc.typeArticlees

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