Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage

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Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage.pdf (8.7 MB)

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2021

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Article

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Artículos Medicina y Ciencias de la Salud

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27

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4
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https://doi.org/10.3390/cells10082159
 http://hdl.handle.net/11447/4537

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Abstract

Niemann-Pick type C disease (NPCD) is a lysosomal storage disorder caused by mutations in the NPC1 gene. The most affected tissues are the central nervous system and liver, and while significant effor...

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Citation

Cells, 2021, vol.10(8):2150

Keywords

Liver damage , Niemann Pick type C disease , Lysosomal storage disorder , Proteomic analysis , Mass spectrometry

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