Bilateral lung disease, extensive and diffuse. Diagnosis of pulmonary alveolar proteinosis by bronchoscopic cryobiopsy

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dc.contributor.authorGando, Sebastian
dc.contributor.authorDure, Roberto
dc.contributor.authorVioli, Damian
dc.contributor.authorVazquez, Bibiana
dc.contributor.authorLabarca, Gonzalo
dc.contributor.authorFernández‐Bussy, Sebastián
dc.date.accessioned2018-01-22T15:05:41Z
dc.date.available2018-01-22T15:05:41Z
dc.date.issued2017
dc.description.abstractPulmonary alveolar proteinosis (PAP) is a rare disease characterized by the intra-alveolar accumulation of a proteinaceous phospholipid-laden material called surfactant. Clinically, this disease should be suspected with respiratory failure in association with a crazy paving pattern on high-resolution chest computed tomography. We report a 24-year-old gentleman who was referred to us for a history of respiratory failure, treatment with invasive ventilation and tracheostomy. His blood exams and biochemistry were normal. His infectious and rheumatological panel was negative for a secondary disease. A flexible bronchoscopy with a transbronchial biopsy through a CryoProbe was performed. An anatomopathological analysis was periodic acid-Schiff positive for PAP. A CryoProbe is a recently developed diagnostic tool that improves the diagnostic yield in diffuse lung diseases compared to bronchoscopy with transbronchial biopsy. This method should be considered for patients with diffuse lung disease and PAP.
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dc.identifier.citationGando S, Duré R, Violi D, Vazquez B, Labarca G, Fernandez-Bussy S. Bilateral lung disease, extensive and diffuse. Diagnosis of pulmonary alveolar proteinosis by bronchoscopic cryobiopsy. Respir Med Case Rep. 2017 Sep 28;22:260-262. doi: 10.1016/j.rmcr.2017.09.010
dc.identifier.urihttp://hdl.handle.net/11447/1932
dc.identifier.urihttp://dx.doi.org/10.1016/j.rmcr.2017.09.010
dc.language.isoen_US
dc.publisherElsevier
dc.sourceRespiratory Medicine Case Reports
dc.subjectPulmonary alveolar proteinosis
dc.subjectCryoProbe
dc.subjectBronchoscopy
dc.titleBilateral lung disease, extensive and diffuse. Diagnosis of pulmonary alveolar proteinosis by bronchoscopic cryobiopsy
dc.typeArtículo

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