Estimulación cerebral profunda en enfermedad de Parkinson

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dc.contributor.authorKunstmann, Carolina
dc.contributor.authorValdivia, Felipe
dc.contributor.authorMarinis, Alejandro de
dc.contributor.authorAyach, Fredy
dc.contributor.authorMontes, José Miguel
dc.contributor.authorChana-Cuevas, Pedro
dc.date.accessioned2022-05-23T20:34:54Z
dc.date.available2022-05-23T20:34:54Z
dc.date.issued2018
dc.description.abstractBackground: Deep brain stimulation is an essential therapeutic tool in Parkinson´s disease. Aim: To assess the results of a series of patients with Parkinson’s disease treated with micro-electrode guided subthalamic nucleus stimulation. Material and Methods: Twenty patients with idiopathic Parkinson’s disease were studied (10 males). Three months after surgery, we analyzed the change in motor disturbances, medication need to control symptoms and quality of life. Results: We observed a significant improvement in all the assessed variables. Motor involvement determined as OFF hours and expressed as percentage of the day changed from 30 ± 15 to 10 ± 7% in the preoperative and postoperative periods, respectively. ON hours without dyskinesia changed from 17 ± 16 to 78 ± 21%. ON hours with dyskinesia changed from 53 ± 23 to 12 ± 15%. Medication need changed from 1,505 ± 499 to 1,214 ± 528 levodopa equivalents. Parkinson’s Disease Questionnaire 39 score changed from 62.9 ± 22.7 to 34.3 ± 18.5. During the 5-year follow-up a continuous improvement of symptoms was observed. Conclusions: Micro-electrode guided subthalamic nucleus functional surgery in patients with Parkinson’s disease has good immediate and late resultses
dc.description.versionVersión Publicadaes
dc.identifier.citationKunstmann Carolina, Valdivia Felipe, De Marinis Alejandro, Ayach Fredy, Montes José Miguel, Chana-Cuevas Pedro. Estimulación cerebral profunda en enfermedad de Parkinson. Rev. méd. Chile [Internet]. 2018 Mayo [citado 2022 Mayo 23] ; 146( 5 ): 562-569. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000500562&lng=es. http://dx.doi.org/10.4067/s0034-98872018000500562.es
dc.identifier.urihttp://dx.doi.org/10.4067/s0034-98872018000500562es
dc.identifier.urihttp://hdl.handle.net/11447/6124
dc.language.isoeses
dc.subjectDeep Brain Stimulationes
dc.subjectParkinson Diseasees
dc.subjectSubthalamic Nucleuses
dc.titleEstimulación cerebral profunda en enfermedad de Parkinsones
dc.title.alternativeDeep brain stimulation in Parkinson's diseasees
dc.typeArticlees
dcterms.sourceRevista Médica de Chilees

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