Chaperone Mediated Autophagy Degrades TDP-43 Protein and Is Affected by TDP-43 Aggregation

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Chaperone Mediated Autophagy Degrades T... and Is Affected by TDP-43 Aggregation.pdf (1.92 MB)

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2020

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Article

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Artículos Medicina y Ciencias de la Salud

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49

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3
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https://doi.org/10.3389/fnmol.2020.00019
 http://hdl.handle.net/11447/4183

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Abstract

TAR DNA binding protein 43 kDa (TDP-43) is a ribonuclear protein regulating many aspects of RNA metabolism. Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD) are fatal n...

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Citation

Frontiers in Molecular Neuroscience, 2020, vol 13, art.19.

Keywords

TARDBP , Protein aggregation , Cellular model , Chaperone mediated autophagy , Lysosomal damage , Amyotrophic lateral sclerosis

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