A liaF codon deletion abolishes daptomycin bactericidal activity against vancomycin-resistant enterococcus faecali

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A liaF Codon Deletion Abolishes Daptomycin Bactericidal Activity against Vancomycin-Resistant.pdf (349.97 KB)

Date

2013

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Artículo

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Artículos Medicina y Ciencias de la Salud

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152

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1
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American Society for Microbiology

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URI

http://hdl.handle.net/11447/1164
 http://dx.doi.org/10.1128/AAC.00021-13

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3

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Abstract

The genetic bases for antibiotic tolerance are obscure. Daptomycin (DAP) is a lipopeptide antibiotic with bactericidal activity against enterococci. Using time-kill assays, we provide evidence for the...

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Citation

Antimicrobial Agents Chemotherapy, 2013,57(6):2831-3

Keywords

Bacterial Proteins/genetics , Codon/genetics , Daptomycin/pharmacology , Drug Resistance, Bacterial/genetics , Enterococcus faecium/drug effects , Sequence Deletion/genetics

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