Managing All the Genotypic Knowledge: Approach to a Septic Patient Colonized by Different Enterobacteriales with Unique Carbapenemases

dc.contributor.authorPark, Stacy C.
dc.contributor.authorWailan, Alexander M.
dc.contributor.authorBarry, Katie E.
dc.contributor.authorVegesana, Kasi
dc.contributor.authorCarroll, Joanne
dc.contributor.authorMathers, Amy J.
dc.contributor.authorMiller, William R.
dc.contributor.authorMunita, José
dc.date.accessioned2022-07-21T16:56:46Z
dc.date.available2022-07-21T16:56:46Z
dc.date.issued2019
dc.description.abstractThe recent development of new antimicrobials active against carbapenemase-producing Enterobacteriales (CPE) has brought new hope for the treatment of infections due to these organisms. However, the evolving epidemiology of bacteria with carbapenemases may complicate management, as providers are faced with treating patients colonized by bacteria producing multiple carbapenemases. Here, we present the clinical course and treatment of Raoultella planticola bacteremia in a cirrhotic patient known to be colonized with both blaKPC- and blaOXA-48-carrying organisms.es
dc.description.versionVersión Publicadaes
dc.identifier.citationPark SC, Wailan AM, Barry KE, Vegesana K, Carroll J, Mathers AJ, Miller WR (commentator), Munita JM (commentator). 2019. Managing all the genotypic knowledge: approach to a septic patient colonized by different Enterobacteriales with unique carbapenemases. Antimicrob Agents Chemother 63:e00029-19. https://doi.org/10 .1128/AAC.00029-19.es
dc.identifier.urihttps://doi.org/10 .1128/AAC.00029-19.es
dc.identifier.urihttp://hdl.handle.net/11447/6377
dc.language.isoenes
dc.relation.projectS.C.P. is supported by the National Institutes of Health (NIH) Infectious Diseases training grant (2T-32AI007046-41). J.M.M. is supported by grants awarded by Comision Nacional de Investigación Científica y Tecnológica (CONICYT), FONDECYT regular grant 1171805, and the Millennium Science Initiative of the Ministry of Economy, Development and Tourism, Government of Chile. W.R.M. is supported by a K08 AI135093 award from NIH/NIAID. W.R.M. has received grants from Merck and Entasis Therapeutics and honoraria from Achaogen and Shionogi.
dc.subjectXA-48es
dc.subjectRaoultella planticolaes
dc.subjectCarbapenem-resistant Enterobacteriales (CRE)es
dc.subjectCarbapenemase-producing Enterobacteriales (CPE)es
dc.subjectCeftazidime-avibactames
dc.titleManaging All the Genotypic Knowledge: Approach to a Septic Patient Colonized by Different Enterobacteriales with Unique Carbapenemaseses
dc.typeArticlees
dcterms.sourceAntimicrobial Agents and Chemotheraphyes

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