Managing All the Genotypic Knowledge: Approach to a Septic Patient Colonized by Different Enterobacteriales with Unique Carbapenemases
Date
2019
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Article
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Abstract
The recent development of new antimicrobials active against carbapenemase-producing Enterobacteriales (CPE) has brought new hope for the treatment of infections due to these organisms. However, the evolving epidemiology of bacteria with carbapenemases may complicate management, as providers are faced with treating patients colonized by bacteria producing multiple carbapenemases. Here, we present the clinical course and treatment of Raoultella planticola bacteremia in a cirrhotic patient known to be colonized with both blaKPC- and blaOXA-48-carrying organisms.
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Citation
Park SC, Wailan AM, Barry KE, Vegesana K, Carroll J, Mathers AJ, Miller WR (commentator), Munita JM (commentator). 2019. Managing all the genotypic knowledge: approach to a septic patient colonized by different Enterobacteriales with unique carbapenemases. Antimicrob Agents Chemother 63:e00029-19. https://doi.org/10 .1128/AAC.00029-19.
Keywords
XA-48, Raoultella planticola, Carbapenem-resistant Enterobacteriales (CRE), Carbapenemase-producing Enterobacteriales (CPE), Ceftazidime-avibactam