Saccadic Direction Errors are Associated with Impulsive Compulsive Behaviours in Parkinson's Disease Patients

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Abstract

Fifteen individuals with Parkinson's disease (PD) and impulsive compulsive behaviours (PD+ICB) were compared to 15 PD patients without ICBs (PD-ICB) and 15 healthy controls (HC) on a pro-saccades and an anti-saccades task to assess if ICBs are associated with distinct saccadic abnormalities. PD+ICB made shorter saccades than HC and more direction errors in the anti-saccades task than PD-ICB and HC, suggesting that patients with ICBs have greater difficulty in suppressing automatic saccades towards a given target. Saccadic assessment has the potential to evolve into a marker to guide therapeutic decisions in patients at risk of developing ICBs.

Description

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Citation

Barbosa P, Kaski D, Castro P, Lees AJ, Warner TT, Djamshidian A. Saccadic Direction Errors are Associated with Impulsive Compulsive Behaviours in Parkinson's Disease Patients. J Parkinsons Dis. 2019;9(3):625-630. doi:10.3233/JPD-181460

Keywords

Parkinson’s disease, Eye movements, Impulse control disorders, Impulsive compulsive behaviours., Sacadles

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