Activation of Electrophile/Nucleophile Pair by a Nucleophilic and Electrophilic Solvation in a SNAr Reaction

dc.contributor.author	Sánchez, Bruno
dc.contributor.author	Calderon, Cristian
dc.contributor.author	Tapia, Ricardo A.
dc.contributor.author	Contreras, Renato
dc.contributor.author	Campodónico, Paola
dc.date.accessioned	2021-08-27T15:53:11Z
dc.date.available	2021-08-27T15:53:11Z
dc.date.issued	2018
dc.description.abstract	Nucleophilic aromatic substitution reactions of 4-chloroquinazoline toward aniline and hydrazine were used as a model system to experimentally show that a substrate bearing heteroatoms on the aromatic ring as substituent is able to establish intramolecular hydrogen bond which may be activated by the reaction media and/or the nature of the nucleophile.	es
dc.identifier.citation	Frontiers in Chemistry. 2018; 6: 509.	es
dc.identifier.uri	https://doi.org/10.3389/fchem.2018.00509	es
dc.identifier.uri	http://hdl.handle.net/11447/4502
dc.language.iso	en	es
dc.subject	Solvent effects	es
dc.subject	Ionic liquids	es
dc.subject	Catalysis	es
dc.subject	Anion effect	es
dc.subject	Preferential solvation	es
dc.title	Activation of Electrophile/Nucleophile Pair by a Nucleophilic and Electrophilic Solvation in a SNAr Reaction	es
dc.type	Article	es

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