Activation of Electrophile/Nucleophile Pair by a Nucleophilic and Electrophilic Solvation in a SNAr Reaction

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Activation of ElectrophileNucleophile Pair by a Nucleophilic and Electrophilic Solvation in a SNAr Reaction.pdf (1.06 MB)

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2018

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Article

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Artículos Medicina y Ciencias de la Salud

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https://doi.org/10.3389/fchem.2018.00509
 http://hdl.handle.net/11447/4502

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Abstract

Nucleophilic aromatic substitution reactions of 4-chloroquinazoline toward aniline and hydrazine were used as a model system to experimentally show that a substrate bearing heteroatoms on the aromatic...

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Citation

Frontiers in Chemistry. 2018; 6: 509.

Keywords

Solvent effects , Ionic liquids , Catalysis , Anion effect , Preferential solvation

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