Association of retinal detachment with age 50 years or younger at onset in patients with acute retinal necrosis

Simple item page
dc.contributor.authorUrzúa, Cristhian
dc.contributor.authorKnickelbein, Jared
dc.contributor.authorCuitino, Loreto
dc.contributor.authorMoreno, Uriel
dc.contributor.authorAnguita, Rodrigo
dc.contributor.authorVelásquez, Víctor
dc.contributor.authorConcha, Luz Elena
dc.contributor.authorMorales, Sergio
dc.contributor.authorVillarroel, Francisco
dc.contributor.authorSen, H Nida
dc.contributor.authorArellanes, Lourdes
dc.date.accessioned2022-04-01T15:38:10Z
dc.date.available2022-04-01T15:38:10Z
dc.date.issued2021
dc.description.abstractBackground Due to the guarded prognosis of acute retinal necrosis (ARN), it is relevant to develop a strategy to earlycategorize those patients in a higher risk of worse outcomes. The purpose of this study is to describe clinical features andpredictive factors for retinal detachment (RD) in patients with ARN. Methods Retrospective observational case series of 34 adult patients (38 eyes) with ARN examined between January 2005 and July 2015 in the National Eye Institute (Bethesda, USA), the Department of Ophthalmology, University of Chile (Santiago, Chile), and APEC (CDMX, Mexico). Results A total of 16 males and 18 females with a mean age at presentation of 44.5±16.8 years were included. Twentyseven patients (79.4%) received intravenous acyclovir as frst-line treatment, and 7 patients received either oral antiviral (4 patients) or oral plus intravitreal antiviral (3 patients). All subjects were treated with prednisone, with a mean initial dose of 57.7±16.3 mg per day. Seventeen patients (50.0%) developed retinal detachment. An association of retinal detachment with age at onset was observed (p=0.04), with patients younger than 50 years presenting a higher risk (OR=14.86, p=0.0009). Additionally, patients in this higher risk group had more infammation in both anterior chamber and vitreous (p=0.04 and 0.03, respectively). No other predictive factor for retinal detachment was found in the present study. Conclusions RD represents an important complication in patients with ARN. Younger patients may be at higher risk of this complication, possibly secondary to the presence of a higher level of infammation.es
dc.description.versionVersión publicadaes
dc.identifier.citationrzua CA, Knickelbein J, Cuitino L, Moreno U, Anguita R, Velasquez V, Concha-Del-Rio LE, Morales S, Villarroel FA, Sen HN, Arellanes-Garcia L. Association of retinal detachment with age 50 years or younger at onset in patients with acute retinal necrosis. Graefes Arch Clin Exp Ophthalmol. 2021 Oct;259(10):2905-2911. doi: 10.1007/s00417-021-05166-4es
dc.identifier.urihttps://doi.org/10.1007/s00417-021-05166-4es
dc.identifier.urihttp://hdl.handle.net/11447/5890
dc.language.isoenes
dc.subjectAcute retinal necrosises
dc.subjectPredictive factorses
dc.subjectRetinal detachmentes
dc.subjectYounger agees
dc.titleAssociation of retinal detachment with age 50 years or younger at onset in patients with acute retinal necrosises
dc.typeArticlees
dcterms.sourceGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie.es

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Association of retinal detachment with age 50.pdf
Size:
621.54 KB
Format:
Adobe Portable Document Format
Description:
Texto completo
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services