Renal peritumoral adipose tissue undergoes a browning process and stimulates the expression of epithelial-mesenchymal transition markers in human renal cells

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Renal peritumoral adipose tissue undergoes a browning process and stimulates the expression of epithelial-mesenchymal transition markers in human renal cells.pdf (3.05 MB)

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2022

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Article

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Artículos Medicina y Ciencias de la Salud

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12

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2
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https://doi.org/10.1038/s41598-022-12746-9

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https://repositorio.udd.cl/handle/11447/7073

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Abstract

Tumor cells can interact with neighboring adipose cells and adipocyte dedifferentiation appears to be an important aspect of tumorigenesis. We evaluated the size of adipocytes in human adipose explant...

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Citation

Ferrando M, Bruna FA, Romeo LR, Contador D, Moya-Morales DL, Santiano F, Zyla L, Gomez S, Lopez-Fontana CM, Calvo JC, Carón RW, Toneatto J, Pistone-Creydt V. Renal peritumoral adipose tissue undergoes a browning process and stimulates the expression of epithelial-mesenchymal transition markers in human renal cells. Sci Rep. 2022 May 23;12(1):8687. doi: 10.1038/s41598-022-12746-9

Keywords

Adipose Tissue / metabolism , Adipose Tissue, Brown / metabolism , Adipose Tissue, White / metabolism , Cadherins / metabolism , Epithelial-Mesenchymal Transition , Kidney Neoplasms / genetics , Kidney Neoplasms / metabolism

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