Publication: Genomic analysis of AlphaFold2-predicted structures identifies maps of 3D essential sites in 243 neurodevelopmental disorder-associated proteins
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Abstract
We propose a new methodology to identify maps of essential sites (i.e., amino acid residues) in 3D, called Essential 3D sites.
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Sumaiya Iqbal, Tobias Brünger, Eduardo Pérez-Palma, David Hoksza, Arthur J. Campbell, Mark J. Daly, Patrick May, Dennis Lal, Genomic analysis of AlphaFold2-predicted structures identifies maps of 3D essential sites in 243 neurodevelopmental disorder-associated proteins, Biophysical Journal, Volume 121, Issue 3, Supplement 1, 2022, Pages 165a-166a, ISSN 0006-3495, https://doi.org/10.1016/j.bpj.2021.11.1909
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