Publication:
Genomic analysis of AlphaFold2-predicted structures identifies maps of 3D essential sites in 243 neurodevelopmental disorder-associated proteins

Date

2022

Authors

Iqbal, Sumaiya
Brunger, Tobias
Hoksza, David
Campbell, Arthur
Daly, Mark
May, Patrick
Lal, Dennis

Journal Title

Journal ISSN

Volume Title

Publisher

Research Projects

Organizational Units

Journal Issue

Abstract

We propose a new methodology to identify maps of essential sites (i.e., amino acid residues) in 3D, called Essential 3D sites.

Description

Keywords

Genomic AlphaFold2

Citation

Sumaiya Iqbal, Tobias Brünger, Eduardo Pérez-Palma, David Hoksza, Arthur J. Campbell, Mark J. Daly, Patrick May, Dennis Lal, Genomic analysis of AlphaFold2-predicted structures identifies maps of 3D essential sites in 243 neurodevelopmental disorder-associated proteins, Biophysical Journal, Volume 121, Issue 3, Supplement 1, 2022, Pages 165a-166a, ISSN 0006-3495, https://doi.org/10.1016/j.bpj.2021.11.1909