Publication: Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria
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3 p.
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Abstract
β-Glucocerebrosidase (GCase) mutations lead to glucosylceramide build-up in the lysosome, impacting α-synuclein aggregation and autophagy. Recently, Baden and colleagues found GCase in mitochondria, s...
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Klein, A.D., Outeiro, T.F. Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria. Nat Commun 14, 6383 (2023). https://doi.org/10.1038/s41467-023-42107-7
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