Publication:
Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis

dc.contributor.authorCorral, Sebastian
dc.contributor.authorGaspar, Pablo A.
dc.contributor.authorCastillo-Passi, Rolando
dc.contributor.authorMayol Troncoso, Rocío
dc.contributor.authorMundt, Adrian P.
dc.contributor.authorIgnatyev, Yuriy
dc.contributor.authorNieto, Rodrigo R.
dc.contributor.authorFigueroa-Muñoz, Alicia
dc.date.accessioned2025-02-25T19:52:16Z
dc.date.available2025-02-25T19:52:16Z
dc.date.issued2024
dc.description.abstractBackground Cognitive alterations have been reported in early stages of psychosis including people with First Episode Psychosis (FEP), Clinical High-Risk Mental State (CHR), and Psychotic-Like Experience (PLE). This study aimed to compare the cognitive function in early stages of psychosis using the Montreal Cognitive Assessment (MoCA), a low-cost and brief assessment tool of cognitive functions. Methods A total of 154 individuals, including 35 with FEP, 38 CHR, 44 PLE, and 37 healthy controls (HC), were evaluated with the MoCA in Santiago, Chile. We calculated the mean total score of the MoCA and the standard deviation of the mean. Groups were assessed for a trend to lower scores in a pre-determined sequence (HC > PLE > CHR > FEP) using the Jonckheere-Terpstra test (TJT). Results The mean total MoCA scores were 24.8 ± 3.3 in FEP, 26.4 ± 2.4 in CHR, 26.4 ± 2.3 in PLE, and 27.2 ± 1.8 in HC. The analyses revealed a significant trend (p < 0.05) toward lower MoCA individual domain scores and MoCA total scores in the following order: HC > PLE > CHR > FEP. The mean total scores of all groups were above the cut-off for cognitive impairment (22 points). Conclusions The MoCA describes lower scores in cognition across early stages of psychosis and may be a useful low-cost assessment instrument in early intervention centers of poorly resourced settings.
dc.description.versionVersión publicada
dc.format.extent5 p.
dc.identifier.citationCorral S, Gaspar PA, Castillo-Passi RI, Mayol Troncoso R, Mundt AP, Ignatyev Y, Nieto RR, Figueroa-Muñoz A. Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis. Schizophr Res Cogn. 2024 Jan 29;36:100302. doi: 10.1016/j.scog.2024.100302. PMID: 38323136; PMCID: PMC10844107.
dc.identifier.doihttps://doi.org/10.1016/j.scog.2024.100302
dc.identifier.urihttps://hdl.handle.net/11447/9848
dc.language.isoen
dc.subjectSchizophrenia
dc.subjectFirst episode psychosis
dc.subjectPsychotic-like experiences
dc.subjectMoCA
dc.subjectNeurocognitive impairment
dc.subjectNeuropsychological assessment
dc.titleMontreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis
dc.typeThesis
dcterms.accessRightsAcceso abierto
dcterms.sourceSchizophrenia Research: Cognition
dspace.entity.typePublication

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