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Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome

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Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome.pdf (5.87 MB)

Date

2023

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Article

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Artículos Medicina y Ciencias de la Salud

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29

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4
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https://doi.org/10.1016/j.xcrm.2023.101035

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https://hdl.handle.net/11447/8673

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Abstract

The transgenerational maternal effects of polycystic ovary syndrome (PCOS) in female progeny are being revealed. As there is evidence that a male equivalent of PCOS may exists, we ask whether sons bor...

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Citation

Risal S, Li C, Luo Q, Fornes R, Lu H, Eriksson G, Manti M, Ohlsson C, Lindgren E, Crisosto N, Maliqueo M, Echiburú B, Recabarren S, Petermann TS, Benrick A, Brusselaers N, Qiao J, Deng Q, Stener-Victorin E. Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome. Cell Rep Med. 2023 May 16;4(5):101035. doi: 10.1016/j.xcrm.2023.101035

Keywords

Adipose tissue , Male offspring , Male offspring to male germline , maternal hyperandrogenism , Maternal obesity , Polycystic ovary syndrome , Small non-coding RNAs , Sperm

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