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Item Biomarcadores Salivales en Pacientes Diagnosticados con Fibrosis Quística, Concepción, 2016(01/05/2018) Gaete O., Fernanda; Astudillo R., Edgardo; Rojas E., Bastián; Narváez Carrasco, CarmenEl odontólogo como profesional integral del área de la salud, debe tener conocimiento acerca de distintas manifestaciones bioquímicas que pueden tener repercusión en la cavidad oral. El objetivo del trabajo fue determinar las manifestaciones bioquímicas y alteraciones en biomarcadores salivales en la cavidad oral producto de la fibrosis quística o del consumo crónico de medicamentos para el tratamiento de la FQ. Se seleccionó un total de cinco personas con fibrosis quística y cuatro personas sanas, pertenecientes a la ciudad de Concepción en la Octava Región de Chile. Se midió pH salival, capacidad buffer, concentración de proteínas totales, tasa de flujo salival estimulado y se determinó presencia de ciertas enzimas salivales en pacientes que padecen la enfermedad. Se pudo evidenciar que el pH salival en sujetos con fibrosis quística tiende a ser mayor a los valores de referencia, la tasa de flujo salival es mucho menor al igual que la capacidad buffer, la concentración de proteínas totales en saliva se encuentra igual a los valores de referencia y se determinó la presencia biomarcadores salivales a través de la técnica de electroforesis. La fibrosis quística afecta de muchas formas a las personas que la padecen, genera cambios a nivel de los biomarcadores salivales como también en la cavidad oral, por lo que el odontólogo debe estar capacitado para identificar estos cambios y poder tratar de la mejor manera a todo tipo de paciente.Item How distributed processing produces false negatives in voxel-based lesion deficit analyses(01/06/2018) Gajardo-Vidal, Andrea; Lorca-Puls, Diego L.; Crinion, Jennifer; White, Jitrachote; Seghier, Mohamed L.; Leff, Alex P.; Hope, Thomas M.H.; Ludersdorfer, Philipp; Green, David W.; Bowman, Howard; Price, Cathy J.In this study, we hypothesized that if the same deficit can be caused by damage to one or another part of a distributed neural system, then voxel-based analyses might miss critical lesion sites because preservation of each site will not be consistently associated with preserved function. The first part of our investigation used voxelbased multiple regression analyses of data from 359 right-handed stroke survivors to identify brain regions where lesion load is associated with picture naming abilities after factoring out variance related to object recognition, semantics and speech articulation so as to focus on deficits arising at the word retrieval level. A highly significant lesion-deficit relationship was identified in left temporal and frontal/premotor regions. Post-hoc analyses showed that damage to either of these sites caused the deficit of interest in less than half the affected patients (76/162=47%). After excluding all patients with damage to one or both of the identified regions, our second analysis revealed a new region, in the anterior part of the left putamen, which had not been previously detected because many patients had the deficit of interest after temporal or frontal damage that preserved the left putamen. The results illustrate how (i) false negative results arise when the same deficit can be caused by different lesion sites; (ii) some of the missed effects can be unveiled by adopting an iterative approach that systematically excludes patients with lesions to the areas identified in previous analyses, (iii) statistically significant voxel-based lesion-deficit mappings can be driven by a subset of patients; (iv) focal lesions to the identified regions are needed to determine whether the deficit of interest is the consequence of focal damage or much more extensive damage that includes the identified region; and, finally, (v) univariate voxel-based lesiondeficit mappings cannot, in isolation, be used to predict outcome in other patients.Item Proteínas Totales, Fosfatasa Alcalina, Prostaglandinas E2 y Lisozima como biomarcadores Salivales en Pacientes Adultos con Periodontitis Crónica(01/12/2017) Romero R., Camila; Suarez M., Mara; Narváez Carrasco, Carmen GloriaLa periodontitis cr nica es una inflamaci n de los tejidos que rodean y dan soporte a los dientes. Diversos biomarcadores qu micos y pro inflamatorios est n aumentados durante el transcurso de la enfermedad. El objetivo del estudio fue determinar los distintos niveles salivales de prote nas totales, fosfatasa alcalina, prostaglandina E2 (PGE2) y lisozima en pacientes con periodontitis cr nica. Se obtuvieron muestras de saliva de 31 pacientes con periodontitis cr nica y se realiz un estudio de serie de casos para la determinaci n cuantitativa de los biomarcadores. La concentraci n de prote nas totales se encontr por sobre los rangos de referencia en 22 pacientes, la actividad de la fosfatasa alcalina se vio aumentada en 9 pacientes y la concentraci n de PGE2 se vio por sobre los rangos de referencia en 30 pacientes. Las prote nas totales y PGE2 son biomarcadores salivales en estos pacientes con periodontitis, no as la fosfatasa alcalina y la lisozima.Item MALNUTRICIÓN POR EXCESO Y RIESGO CARDIOMETABÓLICO EN ESCOLARES DE SEGUNDO Y TERCERO MEDIO DE LA COMUNA DE LOTA DE CHILE(2011) Buhring B., Kristian; Oliva M., Patricio; Villablanca A., Claudia; Rifo M., ValeriaLa malnutrición por exceso en el adolescente es un problema prevalente y aumenta el riesgo de desarrollar enfermedades metabólicas. El objetivo de este estudio fue asociar el síndrome metabólico y el riesgo cardiovascular en escolares de la comuna de Lota de Chile. Estudio de corte transversal, muestreo probabilístico aleatorio simple, se tomó una muestra de 286 niños, de 14 y 18 años de edad. Se estableció la prevalencia de malnutrición, y se realizó una correlación de Pearson. Las correlaciones fueron: peso y talla de 0.55; peso y circunferencia de cintura 0,87; el peso y el índice de masa corporal de 0,86; la talla y la circunferencia de cintura de 0,39; la talla e índice de masa corporal de 0,047; índice de masa corporal y circunferencia de cintura 0,80. El índice de masa corporal, la circunferencia de cintura y el peso, se agrupan en un diagnóstico efectivo. El síndrome metabólico posee una relación que condiciona la presencia de patologías nutricionales, significa que los indicadores antropométricos pueden ser adecuados para identificar la presencia de riesgo cardiometabólico en adolescentes.Item Problemas de adherencia a dietoterapia en pacientes hipertensos Pehuenches(2011) Oliva, Patricio; Buhring, KristianBackground: Hypertension is a disease with a high national prevalence which increases in sectors where there are indigenous populations. The complexity of the disease lies in the behavior that must be maintained to effectively adhere to medication and diet therapy. Objective: To understand the cultural factors that are associated with problems of adherence to diet therapy in hypertensive pehuenches. Methods: Qualitative study in hypertensive patients who do not adhere to diet therapy. We interviewed 42 individuals in the municipality of Alto Bio Bio for 6 months, analyzing them using semantic structural analysis completed with the saturation point of speech. Results: Discourse analysis showed the following results: a) ethnic foods have a symbolic value, b) ethnic foods are described as “natural” in opposition to any food that does not occur in their environment, although they are based in a high consumption of fats, proteins and carbohydrates, c) nonexistent biochemical properties ascribed to ethnic foods justify their use. Conclusion: there are cultural differences between the prescription of the nutritionist and the eating behavior of pehuenches, which affect non-compliance with diet and disease complications.Item Evaluación de una intervención en actividad física en niños con síndrome de Down(2011) Mosso C., Constanza; Santander V., Patricia; Pettinelli R., Paulina; Valdés G., Marcela; Celis B., Magdalena; Espejo S., Fabián; Navarro M., Lecter; Sepúlveda V., FranciscoIntroducción: En Chile no existen estudios acerca del efecto de la actividad física sobre el estado nutricional en niños con síndrome de Down. Objetivo: Conocer el estado nutricional en niños con síndrome de Down y la capacidad aeróbica y resistencia al esfuerzo muscular antes y después de una intervención en actividad física. Material y Método: Entre agosto y noviembre del año 2006, en un grupo de 18 niños (10 hombres y 8 mujeres) con síndrome de Down, con edades comprendidas entre 5 - 9 años, se desarrolló un estudio de intervención en actividad física de 12 semanas, realizándose una evaluación diagnóstica y una evaluación final de resistencia muscular (dorsal, abdominal y cuádriceps) y capacidad aeróbica. Se evaluó el estado nutricional a través de P/E y T/E (Fundación Catalana), IMC, IP/T y porcentaje de masa grasa. Resultados: Se observaron diferencias significativas en resistencia muscular, capacidad aeróbica, IP/T y circunferencia de cintura entre el pre-test y post-test (p < 0,05). Al inicio de la intervención un 53% presentaba exceso de peso según IMC, un 26% según P/E y un 68% según IP/T; con un porcentaje masa grasa fue de 22,6%. Conclusión: Aunque el tiempo de intervención fue breve, se observó una mejora significativa en la resistencia muscular, capacidad aeróbica, IP/T y circunferencia de cintura. De acuerdo a nuestros resultados, existe una alta prevalencia de malnutrición por exceso en esta población de niños con SD en la que se hace vital intervenir con una actividad física adecuadaItem Tutorías virtuales como herramienta complementaria y su efecto sobre las evaluaciones globales en estudiantes universitarios(2011) Guzmán Castro, Andrea ElizabethEste estudio persiguió determinar el efecto de las tutorías virtuales (TV) como herramienta complementaria sobre las calificaciones globales en estudiantes universitarios. A partir del universo, se extrajo una muestra no probabilística de 44 estudiantes; el control fue el mismo grupo previo a la intervención pedagógica. Las TV comenzaron posterior a la primera evaluación global y hasta finalizar el curso, utilizando la herramienta "Grupos Google©". Se recolectaron calificaciones global 1 (sin tutoría virtual) y global 2 (con tutoría virtual), datos analizados descriptivamente y mediante t-test para muestras dependientes. Los resultados muestran que las TV como herramienta complementaria, mejoran significativamente las calificaciones de las evaluaciones globales de los estudiantes que la utilizan (p < 0,01). Adicionalmente, se evidenció un patrón en la frecuencia de participación de los estudiantes, que se relacionaría con la cercanía a fechas evaluativas. Es necesario que las instituciones de educación superior promuevan prácticas educativas innovadoras que favorezcan el aprendizajeItem Electromyographic activity of the sphenomandibularis and lateral pterygoid human muscles during mandibular lateral movements(2012) Fuentes, Edgardo; Frugone, Raúl; Paolinelli, C; Hack, G D; Bittner, VAim. Understanding of the functional anatomy of the Sphenomandibularis muscle (SM) is limited. In order to begin to elucidate its function, the present authors determined, using electromyographic evaluations, that the (SM) displays signifcantly more electromyographic (EMG) activity (during jaw movement excursions from edge to edge to maximal intercuspation with occlusive force), than does the lateral pterygoid muscle. Methods. A descriptive, non-experimental study was conducted. Electromyographic recordings were performed with depth electrodes during movements of the mandible, both with and without occlusal contact. Five male subjects between 18 and 27 years of age underwent electromyographic study of the SM and lateral pterygoid muscles. EM activity was observed to occur only in the lateral pterygoid muscle (and not the SM), during lateral movements, with and without tooth contact, on a working side movement. Results. During both contralateral movements, without tooth contact, and also during ipsilateral movements with forced occlusal contact, we observed an increase in the SM only. During mandibular movements, from lateral to medial with forced occlusal contact, we observed strong EM activity in both muscles, with the EM activity being greater in the SM. Conclusion. The authors conclude that the SM is a lateral pterygoid agonist; coming into play during the last phase of mastication, and may play an important role in eccentric bruxismItem Percepción de rendimiento académico en estudiantes de Odontología(2013) Oliva Mella, Patricio; Narváez, Carmen GloriaLa investigación se centra en la percepción del rendimiento académico de estudiantes de pregrado de Odontología de la Universidad del Desarrollo, Concepción, Chile, contrastándola con distintas variables vinculadas a este concepto, con el objetivo de establecer una visión completa por medio de las asociaciones estadísticas existentes entre ellas. La investigación es de tipo cuantitativo, comparativo, transversal, se utilizó una encuesta validada por expertos y mediante un pilotaje, de la cual derivó una base de datos analizada mediante el programa SPSS®. Los datos tienen una distribución paramétrica, utilizando el test de Kolmogorov-Smirnov, posteriormente se aplica la prueba de t-Student. Los resultados demuestran que la percepción del redimiendo académico se vincula con variables que se asocian al propio estudiante y a variables que son consideradas exógenas por ellos. Se concluye que la percepción del rendimiento es una construcción socio-educacional constituida por múltiples variables que interaccionan y redundan en un resultado de calificación formal.Item Nutrition assessment and indicators of visceral fat and subcutaneous fat in children with Down syndrome(2015) Venegas, E; Ortiz, T; Grandfeltd, G; Zapata, D; Fuenzalida, P; Mosso, CBackground There are only few publications related to body composition in Down syndrome (DS). Objective Evaluate the relationship between indicators of nutrition assessment by Catalan references and CDC/NCHS and indicators of body composition, and compare the concordance between weight/height index (WHI), body mass index/age (BMIa) and weight/age (WA) to evaluate nutritional status in children with DS. Materials and methods Analytical cross-sectional study in which 40 children with DS, 20 girls and 20 boys between 3 and 13 years old were studied. Anthropometric measurements were performed to obtain indicators of nutrition assessment as WHI, BMIa and WA and indicators of subcutaneous and visceral fat and muscular compartment. Correlation tests and Kappa index were evaluated to establish relationship and agreement respectively. Results The nutrition assessment in children with DS shows that 60% presents overweight and obesity according to BMIa, and 75% according to WHI. Correlation analysis indicates that waist circumference, fat brachial area, % fat mass by Slaughter and Weststrate and Deurenberg have a high positive correlation with BMIa (P-value<0.05). A logistic regression model showed that no indicator of fat mass is clinically significant in predicting an increase of the indicator WA. It was determined that the BMIa and WHI indicators have a higher concordance (Kappa=0.59; P=0.0000). Conclusions We determined a high correlation between nutritional diagnosis (BMIa and WA) with indicators of visceral fat (waist circumference) and subcutaneous (% fat mass and fat brachial area) in children with DS. A greater agreement was found between indicators of BMIa and WA suggesting that they are optimal for assessing the nutritional status.Item Efficacy of combined radiotherapy and chemotherapy versus radiotherapy for oral squamous cell carcinoma(2015) Irisarri Arévalo, Jaime; Oliva Mella, PatricioIntroduction: in the last decade, with all the advanced medical research in the treatments for cancer, there is a constant debate for the best possible treatment for oral squamous cell carcinomas. Radiotherapy with surgery has they compared with the addition of chemotherapy for control of the disease or survival of the patient. Objective: to compare the effectiveness of radiotherapy with combined chemotherapy and radiotherapy for the control of oral squamous cell carcinomas. Methods: it was a systematic review with metaanalysis. Randomized trials in all phases were search with specific inclusion criteria through electronic database, hand searching and contacting experts in the field. After exclusion, criteria and the use of critical review checklist, three trials they selected for analysis. Three randomized trials representing 508 patients they identified. Some trials they analyzed in Review manager software 5.0®. The fix effect model they chosen for the statistical analysis, assuming that any observed variation in the score was an error of the specific article, with a confidence of 95 % (CI 1.13–2.77). The I2 presents percent of heterogeneity of 0 %, indicating that there is no clinically significant change in the results of the studies included. Result: evidenced the significance of 0.44 (higher than 0.05) in the chi square test indicating that the results are homogeneous or clinically similar. The Forest plot is located in the experimental group (chemotherapy and radiotherapy), establishing the clinical recommendation of use. Conclusion: the usage of chemotherapy treatment in combination of radiotherapy regimen they recommended as for its promising results. Not also, the overall survival has improved, survival and distant metastasis free rates improve.Item Dietary intake, Body Composition, and Physical Activity among Young Patients with Type 1 Diabetes Mellitus(2015) Mosso, Constanza; Halabi, Victoria; Ortiz, Tamara; Hodgson, María IsabelObjective: The aim of this study was to assess dietary intake, nutritional status, body composition, and physical activity level in a group of Chilean children and adolescents with Type 1 diabetes mellitus (T1DM), compare these parameters with the recommendations of the International Society for Pediatric and Adolescent Diabetes (ISPAD), and determine the relationships between dietary intake, body composition, and diabetes control. Methods: A total of 30 patients with T1DM (aged 15.2 +/- 4.0 years) were included. Dietary intake was assessed using a 92-item quantitative food frequency questionnaire. Body composition was determined using dual-energy X-ray densitometry. Physical activity was assessed by means of a survey. Results: The energy intake of these patients was derived from 21.4% protein, 48% carbohydrates, and 31.2% fat. The glycosylated hemoglobin (HbA(1c)) was significantly correlated with fat as grams per day (r: 0.363, p < 0.05) and calories per day (r: 0.364, p < 0.05). The mean body fat percentage in females was 31.2% and 20.2% in males (p < 0.01) and the mean amount of physical activity was 4.5 +/- 2.7 h per week. Conclusions: The study patients had a higher protein intake than recommended by ISPAD. Dietary carbohydrate intake was rather low, and dietary fat intake was the same as the limits recommended by ISPAD. Diabetic control was significantly correlated with protein, carbohydrates, fat, and sodium intake. The girls in the study had a higher percentage of body fat than the standard recommendations for their age. The level of physical activity was adequate.Item Computer-guided implant surgery and immediate loading with a modifiable radiographic template in a patient with partial edentulism: A clinical report(2015) Lanis, Alejandro; Padial-Molina, Miguel; Gamil, Rami; Alvarez del Canto, OrlandoComputer-guided implant surgery in fresh extraction sites is an underdeveloped procedure. The presence of teeth that will be extracted makes the creation of an appropriate radiographic template for virtual simulation of the rehabilitation impossible. A modified radiographic template is presented to define a digital restorative simulation for the maxillary rehabilitation of a patient with partial edentulism. This modification enables 3-dimensional prosthetic virtual information in regions where teeth will be extracted.Item Maternal supraphysiological hypercolesterolemia leads to endothelial dysfunction of the human fetoplacental macro and microvasculature(2015) Leiva, Andrea; Salsoso, Rocío; Sáez, Tamara; Silva, Luis; Sanhueza, Carlos; Pardo, Fabian; Sobrevía, LuisMaternal physiological hypercholesterolemia (MPH) occurs in pregnancy assuring fetal growth and development. However, maternal supraphysiological hypercholesterolemia (MSPH) leads to increased atherosclerosis in the fetal vasculature. In this study the maternal and neonatal total cholesterol (TCh) and lipoprotein levels were determined in a group of pregnant women and her newborns. A cut-off value for MSPH was established as maternal TCh levels at term of pregnancy >280 mg/dl. Pregnancies with values over this cut-off point were associated with fetoplacental endothelial dysfunction evaluated as reduced endothelial-dependent vascular dilation in the macro- (umbilical vein; 41 ± 7% and 10± 2% for MPH and MSPH, respectively) and microvasculature (veins in placental stem villi; 52 ± 6% and 1± 0.2% for MPH and MSPH, respectively). The mechanisms involved in this phenomenon include reduced nitric oxide synthase (NOS) activity and therefore reduced nitric oxide (NO) availability in human umbilical vein endothelial cells (HUVEC; reduction of 51 ± 2% compared with MPH) and human placental microvascular endothelial cells (HPMEC; reduction of 83 ± 4% compared with MPH). MSPH was also associated with reduced synthesis of the eNOS cofactor tetrahydrobiopterin (BH4; reduction of 87.5 ± 5% compared with MPH) as well as increased activity of arginases, a group of enzymes that compete with NOS for the substrate L-arginine (1.5 times compared with MPH). Interestingly, the restoration of the BH4 levels and the inhibition of arginases improved the endothelial function impaired by the MSPH condition. Therefore MSPH is a maternal condition likely involved in the endothelial dysfunction and the later development of atherosclerosis described for MSPH offspring. However, the mechanism(s) leading to the development MSPH as well as whether this maternal condition modifies the placental transport of cholesterol and therefore the fetal lipid function are actually unknown.Item Growth Factors for Treating Diabetic Foot Ulcers(2015) Marti-Carvajal, Arturo; Gluud, Christian; Nicola, Susana; Simancas-Racines, Daniel; Reveiz, Ludovic; Oliva Mella, Patricio; Cedeno-Taborda, JorgeBackground Foot ulcers are a major complication of diabetes mellitus, often leading to amputation. Growth factors derived from blood platelets, endothelium, or macrophages could potentially be an important treatment for these wounds but they may also confer risks. Objectives To assess the benefits and harms of growth factors for foot ulcers in patients with type 1 or type 2 diabetes mellitus. Search methods In March 2015 we searched the Cochrane Wounds Group Specialised Register, The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library), Ovid MEDLINE, Ovid MEDLINE (In-Process & Other Non-Indexed Citations, Ovid EMBASE and EBSCO CINAHL. There were no restrictions with respect to language, date of publication or study setting. Selection criteria Randomised clinical trials in any setting, recruiting people with type 1 or type 2 diabetes mellitus diagnosed with a foot ulcer. Trials were eligible for inclusion if they compared a growth factor plus standard care (e.g., antibiotic therapy, debridement, wound dressings) versus placebo or no growth factor plus standard care, or compared different growth factors against each other. We considered lower limb amputation (minimum of one toe), complete healing of the foot ulcer, and time to complete healing of the diabetic foot ulcer as the primary outcomes. Data collection and analysis Independently, we selected randomised clinical trials, assessed risk of bias, and extracted data in duplicate. We estimated risk ratios (RR) for dichotomous outcomes. We measured statistical heterogeneity using the I2 statistic. We subjected our analyses to both fixedeffect and random- effects model analyses. Main results We identified 28 randomised clinical trials involving 2365 participants. The cause of foot ulcer (neurologic, vascular, or combined) was poorly defined in all trials. The trials were conducted in ten countries. The trials assessed 11 growth factors in 30 comparisons: platelet-derived wound healing formula, autologous growth factor, allogeneic platelet-derived growth factor, transforming growth factor beta 2, arginine-glycine-aspartic acid peptide matrix, recombinant human platelet-derived growth factor (becaplermin), recombinant human epidermal growth factor, recombinant human basic fibroblast growth factor, recombinant human vascular endothelial growth factor, recombinant human lactoferrin, and recombinant human acidic fibroblast growth factor. Topical intervention was the most frequent route of administration. All the trials were underpowered and had a high risk of bias. Pharmaceutical industry sponsored 50% of the trials. Any growth factor compared with placebo or no growth factor increased the number of participants with complete wound healing (345/657 (52.51%) versus 167/482 (34.64%); RR 1.51, 95% CI 1.31 to 1.73; I2 = 51%, 12 trials; low quality evidence). The result is mainly based on platelet-derived wound healing formula (36/56 (64.28%) versus 7/27 (25.92%); RR 2.45, 95% 1.27 to 4.74; I-2 = 0%, two trials), and recombinant human platelet-derived growth factor (becaplermin) (205/428 (47.89%) versus 109/335 (32.53%); RR 1.47, 95% CI 1.23 to 1.76, I-2= 74%, five trials). In terms of lower limb amputation (minimum of one toe), there was no clear evidence of a difference between any growth factor and placebo or no growth factor (19/150 (12.66%) versus 12/69 (17.39%); RR 0.74, 95% CI 0.39 to 1.39; I-2 = 0%, two trials; very low quality evidence). One trial involving 55 participants showed no clear evidence of a difference between recombinant human vascular endothelial growth factor and placebo in terms of ulcer-free days following treatment for diabetic foot ulcers (RR 0.64, 95% CI 0.14 to 2.94; P value 0.56, low quality of evidence) Although 11 trials reported time to complete healing of the foot ulcers in people with diabetes, meta-analysis was not possible for this outcome due to the unique comparisons within each trial, failure to report data, and high number of withdrawals. Data on quality of life were not reported. Growth factors showed an increasing risk of overall adverse event rate compared with compared with placebo or no growth factor (255/498 (51.20%) versus 169/332 (50.90%); RR 0.83; 95% CI 0.72 to 0.96; I-2 = 48%; eight trials; low quality evidence). Overall, safety data were poorly reported and adverse events may have been underestimated. Authors' conclusions This Cochrane systematic review analysed a heterogeneous group of trials that assessed 11 different growth factors for diabetic foot ulcers. We found evidence suggesting that growth factors may increase the likelihood that people will have complete healing of foot ulcers in people with diabetes. However, this conclusion is based on randomised clinical trials with high risk of systematic errors (bias). Assessment of the quality of the available evidence (GRADE) showed that further trials investigating the effect of growth factors are needed before firm conclusions can be drawn. The safety profiles of the growth factors are unclear. Future trials should be conducted according to SPIRIT statement and reported according to the CONSORT statement by independent investigators and using the Foundation of Patient-Centered Outcomes Research recommendations.Item The Combination of Digital Surface Scanners and Cone Beam Computed Tomography Technology for Guided Implant Surgery Using 3Shape Implant Studio Software: A Case History Report(2015) Lanis, Alejandro; Alvarez del Canto, OrlandoThe incorporation of virtual engineering into dentistry and the digitization of information are providing new perspectives and innovative alternatives for dental treatment modalities. The use of digital surface scanners with surgical planning software allows for the combination of the radiographic, prosthetic, surgical, and laboratory fields under a common virtual scenario, permitting complete digital treatment planning. In this article, the authors present a clinical case in which a guided implant surgery was performed based on a complete digital surgical plan combining the information from a cone beam computed tomography scan and the virtual simulation obtained from the 3Shape TRIOS intraoral surface scanner. The information was imported to and combined in the 3Shape Implant Studio software for guided implant surgery planning. A surgical guide was obtained by a 3D printer, and the surgical procedure was done using the Biohorizons Guided Surgery Kit and its protocol.Item Valores éticos y formación curricular en odontología(2015) Vicentela, Luis A.; Narváez, Carmen Gloria; Velásquez, ManuelPara identificar los valores éticos de los estudiantes de odontología y relacionarlos con el perfil de egreso, se elaboró una encuesta, aplicada a 1.281 estudiantes de ocho sedes que imparten odontología en Chile. Esta contenía 24 valores y cinco categorías de relevancia, estimando un promedio general por curso y género. En orden de relevancia, valores como felicidad, responsabilidad, sinceridad, respeto y bienestar fueron los más destacados; mientras que innovación, liderazgo, civismo, participación y reconocimiento los menos resaltados. En los primeros, no hay diferencias significativas por curso pero sí por género (p<0,05), excepto en bienestar, mientras que en los menos destacados no hay diferencias significativas por género, pero sí por curso (p<0,05). Del análisis de los perfiles destacan los valores de liderazgo, participación, cooperación y convivencia. Sin embargo, estos se encuentran al final de la escala de preferencia de los alumnos. De los cinco más valorados por los estudiantes, solo responsabilidad y respeto destacan en uno de los perfiles de egreso. En conclusión, los perfiles de egreso profesional deben incorporar valores que fortalezcan el desarrollo ético y tengan en cuenta la impronta valórica de los alumnos, de forma de alinearlos con los definidos por la institución y el propio perfil.Item Relación entre el bienestar y el rendimiento académico en alumnos de primer año de medicina(2015) Gómez, Paula; Torres, Graciela; Meyer, Andrea; Matus, Olga; Ortíz, Liliana; McColl, Peter; Parra, Paula; Pérez, CristhianBackground: Stress may affect the sense of wellbeing and academic achievement of university students. Aim: To assess the relationship of academic engagement and burnout with academic achievement among first year medical students. Material and Methods: The Utrecht Work Engagement Scale-Student and Maslach Burnout Inventory Student Survey (MBI-SS) were applied to 277 first year medical students of four universities. Their results were correlated with the grades obtained in the different courses. Results: Moderately high engagement and low burnout levels were detected. There was a high level of satisfaction with studies and a moderate exhaustion level. Academic achievement was associated with the degree of engagement with studies but not with burnout. Conglomerate analysis detected a group of students with high levels of wellbeing, characterized by high levels of academic engagement and low burnout. Other group had moderate levels of engagement and lack of personal fulfilment. Other group, identified as extenuated, had high levels of personal exhaustion and depersonalization. Finally the disassociated group had a low academic engagement, low emotional exhaustion, high levels of depersonalization and Jack of personal fulfillment. Conclusions: Academic achievement is associated with the level of engagement with studies but not with burnout.Item Bone Mineral Density in Young Chilean Patients with type 1 Diabetes Mellitus(2016) Mosso, Constanza; Hodgson, María Isabel; Ortiz, Tamara; Reyes, María LoretoBackground: In this study, our aim was to analyze bone mineral density (BMD) in patients with type 1 diabetes mellitus (T1DM) and compare them with a healthy reference population; in addition, we aimed to observe the association between BMD and the following variables: age at onset, disease duration, metabolic control, pubertal stage, level of physical activity, clinical parameters and nutrient intake. Methods: A total of 30 patients with T1DM were included in the study. BMD was determined using dual-energy X-ray densitometry (DXA). Participants with a z-score of values >= -1 were accepted as normal; BMDs between -2 and -1 were defined as being in the low range of normality; <= -2 were defined as having low BMD. The 25-hydroxy vitamin D level was classified as sufficient (30-100 ng/mL), insufficient (20-30 ng/mL), and deficient (< 20 ng/mL). Results: The percentages of patients with deficient and insufficient 25(OH) vitamin D levels were 50% and 45.8%, respectively. Lumbar spine (LS2-LS4) BMD, total body (TB) BMD and femoral neck (FN) BMD were found in the normal range for more than 80% of the subjects, with no significant differences due to gender. No strong correlations between clinical variables, biochemical parameters and nutrient intake were observed; however, a moderate positive correlation was found between serum calcium and LS2-LS4 BMD (p < 0.05). Regression analysis showed that serum calcium, duration of diabetes and intake of sodium and protein are significant factors in determining LS2-LS4 BMD and TB BMD. Conclusions: Patients with T1DM had a normal mean BMD at all sites evaluated, except for two patients who had low BMD at the lumbar spine. More than 95% of patients had insufficient or deficient vitamin D levels. With respect to all the variables studied, serum calcium presented the highest significant correlation with LS2-LS4 BMD.Item Valoración del mlearning en el proceso de aprendizaje de estudiantes de la Salud(2016) Oliva Mella, Patricio; Narváez, Carmen Gloria; Buhring Bonacich, KristianIntroducción: la utilización actual y constante de tecnologías en educación ha configurado una nueva dimensión que genera un apoyo constante en el proceso de enseñanza-aprendizaje en educación superior. La aplicación de tecnología de aprendizaje móvil, Mobile learning, dentro del contexto educativo ha establecido nuevos parámetros en la ergonomía educativa facilitándose el acceso continuo a la información. Su posicionamiento genera nuevos paradigmas cuyas valorizaciones deben ser estudiadas de forma adecuada. Objetivo: describir la valoración del mobile learning en el proceso de aprendizaje en alumnos de Salud. Métodos: esta investigación fue de carácter cuantitativa, utilizándose estadística descriptiva. Se recolectó la información mediante encuestas tabulándose en Spss 15 ®. Se obtuvo una muestra de 202 sujetos de carreras de la Facultad de Salud de la Universidad del Desarrollo, Chile. Resultados: los encuestados indicaron que las tecnologías más utilizadas son la laptop (47 %) y el smartphone (42 %), se constituye, además, como las más importantes (laptop con un 56 % y smartphone con un 21 %). Un 28,7 % de quienes utilizan laptop para estudiar la valoran de forma positiva, percepción que baja a un 21 % en la utilización del smartphone (ambas con un p = 0,00). Esta tecnología es utilizada por lo general para buscar información (27 %). Conclusiones: se concluye que las tecnologías móviles adquieren importancia dentro del aprendizaje de los alumnos de educación superior. Las tecnologías tradicionales (pc de escritorio) se utilizan poco. La generación de una red para estudiar es valorada, por lo que la utilización del mobile learning contribuye de forma positiva en el mantenimiento de este tipo de comunicación
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