Charged Residues at the First Transmembrane Region Contribute to the Voltage Dependence of the Slow Gate of Connexins
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American Society for Biochemistry and Molecular Biology by Sage
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Abstract
Connexins (Cxs) are a family of membrane-spanning proteins that form gap junction channels and hemichannels. Connexin-based channels exhibit two distinct voltage-dependent gating mechanisms termed slo...
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Centro de Fisiología Celular e Integrativa
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Pinto BI, García IE, Pupo A, Retamal MA, Martínez AD, Latorre R, González C. Charged Residues at the First Transmembrane Region Contribute to the Voltage Dependence of the Slow Gate of Connexins. J Biol Chem. 2016 Jul 22;291(30):15740-52
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