Características clínicas de 63 pacientes con ataxia
Date
2018
Type:
Article
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Abstract
Background: Ataxia can be classified as genetic, sporadic or acquired.
Aim: To report the clinical features of a group of patients with ataxia. Material
and Methods: Review of medical records of patients consulting in a specialized
center in movement disorders. Those records in which the diagnosis of “ataxia”
or “ataxic syndrome” appeared, were selected for the review. Results: Of 4,282
records surveyed, the diagnosis of ataxia appeared in 95. After eliminating re-
peated or incomplete records, 63 were reviewed. Results: Ataxia was sporadic,
genetic and acquired in 27, 22 and 14 patients, respectively. The mean age at
presentation for genetic, acquired and sporadic ataxia was 24, 46 and 53 years
respectively. All autosomal dominant ataxias were type 3 spinocerebellar ataxia
(SCA). Friedrich’s ataxia was the most common recessive form. Most sporadic
forms of ataxia were multiple system atrophy with predominant cerebellar ataxia
(MSA-C) subtype. Conclusions: Considering the heterogeneity of patients with
ataxia, we propose a method to approach them.
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Citation
Saffie Awad P, Vial Undurraga F, Chaná-Cuevas P. Características clínicas de 63 pacientes con ataxia [Clinical features of 63 patients with ataxia]. Rev Med Chil. 2018 Jun;146(6):702-707. Spanish. doi: 10.4067/s0034-98872018000600702. PMID: 30148901.
Keywords
Cerebellar Ataxia, Friedreich Ataxia, Machado-Joseph Disease, Spinocerebellar Ataxias