Determinación de la reserva ovárica mediante el recuento de folículos antrales en mujeres en edad reproductiva
Date
2017
Type:
Artículo
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6
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Journal Title
Journal ISSN
Volume Title
Publisher
Sociedad Medica de Santiago
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Abstract
Background: Age plays a crucial role in women fertility and is related with a
decreased oocyte quality and quantity. The evidence for this asseveration comes
from data obtained in infertile women. However there is a paucity of studies
in patients with proven fertility evaluating ovarian reserve and its decline with
time. Aim: To measure antral follicle count (AFC) in probed fertile patients
and to create a distribution chart based on variables that may affect its natural
decline. Material and Methods: Observational prospective study. A transvaginal
ultrasound was made between menstrual cycle days 3 and 5, evaluating AFC
in 100 patients, followed during a year. Results: Median antral follicle count
media was 14.5 (interval 3 to 26). There was a lineal decline of AFC with age.
Women with hypertension and type 2 diabetes mellitus had significantly less
follicles. However, a multiple regression analysis showed that only women’s age
was a significant predictor of AFC (R2
= 0.84). Conclusions: There was a lineal
relationship between AFC and age in women with probed fertility.
Description
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Citation
Errázuriz V J, Carrasco Á, Díaz R E, Sanhueza R P, González S P, Donoso P P. Determinación de la reserva ovárica mediante el recuento de folículos antrales en mujeres en edad reproductiva [Association between antral follicle count and age in fertile women]. Rev Med Chil. 2017 Jun;145(6):741-746
Keywords
Fertility, Ovarian follicle, Reproductive Medicine