The basic reproduction number R0 and effectiveness of reactive interventions during dengue epidemics: the 2002 dengue outbreak in Easter Island, Chile.

Simple item page
dc.contributor.authorChowell, G
dc.contributor.authorFuentes, R
dc.contributor.authorOlea, Andrea
dc.contributor.authorAguilera, Ximena
dc.contributor.authorNesse, H
dc.contributor.authorHyman, J
dc.date.accessioned2017-04-06T15:15:05Z
dc.date.available2017-04-06T15:15:05Z
dc.date.issued2013
dc.descriptionCentro de Epidemiología y Políticas de Salud
dc.description.abstractWe use a stochastic simulation model to explore the effect of reactive intervention strategies during the 2002 dengue outbreak in the small population of Easter Island, Chile. We quantified the effect of interventions on the transmission dynamics and epidemic size as a function of the simulated control intensity levels and the timing of initiation of control interventions. Because no dengue outbreaks had been reported prior to 2002 in Easter Island, the 2002 epidemic provided a unique opportunity to estimate the basic reproduction number R0 during the initial epidemic phase, prior to the start of control interventions. We estimated R0 at 27.2 (95%CI: 14.8, 49.3). We found that the final epidemic size is highly sensitive to the timing of start of interventions. However, even when the control interventions start several weeks after the epidemic onset, reactive intervention efforts can have a significant impact on the final epidemic size. Our results indicate that the rapid implementation of control interventions can have a significant effect in reducing the epidemic size of dengue epidemics.
dc.format.extent21
dc.identifier.citationMathematical Biosciences and Engineering, 2013,10(5-6):1455-74
dc.identifier.urihttp://hdl.handle.net/11447/1098
dc.identifier.urihttp://dx.doi.org/10.3934/mbe.2013.10.1455
dc.language.isoen_US
dc.publisherAmerican Institute of Mathematical Sciences
dc.subjectdengue
dc.subjectdengue hemorrhagic fever
dc.subjectepidemic
dc.subjecteaster island
dc.subjectchile
dc.subject2002 outbreak
dc.subjectmathematical model
dc.subjectreproduction number
dc.titleThe basic reproduction number R0 and effectiveness of reactive interventions during dengue epidemics: the 2002 dengue outbreak in Easter Island, Chile.
dc.typeArtículo

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
The basic reproduction number ℛ0 and effectiveness of reactive interventions during dengue epidemics The 2002 dengue outbreak in easter Island, Chile.pdf
Size:
693.52 KB
Format:
Adobe Portable Document Format
Description:
Texto completo
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services