Teneurin protein family: An emerging role in human tumorigenesis and drug resistance

dc.contributor.author	Ziegler, Annemarie
dc.contributor.author	Corvalán, Alejandro
dc.contributor.author	Roa, Iván
dc.contributor.author	Brañes, Jorge
dc.contributor.author	Wollscheid, Bernd
dc.date.accessioned	2021-10-01T19:10:08Z
dc.date.available	2021-10-01T19:10:08Z
dc.date.issued	2012
dc.description.abstract	Using a chemoproteomic strategy, we recently demonstrated the expression of teneurin-2, a transmem-brane glycoprotein, in the majority of malignant mesothelioma cell lines. This finding was unexpected since no formally organized evidence existed to implicate teneurins in human malignancy. For this reason, here we provide a comprehensive review on the expression of teneurins in human tumors and cell lines. Current evidence supports the aberrant expression of teneurins in various tumor types, their involvement in cancer-related regulatory networks, and their potential participation in drug resistance. Structural attributes of teneurins could enable the detection of shedded forms in body fluids for clinical applications.	es
dc.identifier.citation	Cancer Letters, 2012; 326(1):1-7	es
dc.identifier.uri	http://dx.doi.org/10.1016/j.canlet.2012.07.021	es
dc.identifier.uri	http://hdl.handle.net/11447/4759
dc.language.iso	en_US	es
dc.subject	Teneurins	es
dc.subject	Tumor biomarkers	es
dc.subject	Tumorigenesis	es
dc.subject	Drug resistance	es
dc.title	Teneurin protein family: An emerging role in human tumorigenesis and drug resistance	es
dc.type	Article	es

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