Autonomic disturbances in narcolepsy

Simple item page
dc.contributor.authorPlazzi, Giuseppe
dc.contributor.authorMoghadam, Keivan Kaveh
dc.contributor.authorSerra Maggi, Leonardo
dc.contributor.authorDonadio, Vincenzo
dc.contributor.authorVetrugno, Roberto
dc.contributor.authorLiguori, Rocco
dc.contributor.authorZoccoli, Giovanna
dc.contributor.authorPoli, Francesca
dc.contributor.authorPizza, Fabio
dc.contributor.authorPagotto, Uberto
dc.contributor.authorFerri, Raffaele
dc.date.accessioned2021-09-12T03:36:46Z
dc.date.available2021-09-12T03:36:46Z
dc.date.issued2011
dc.description.abstractNarcolepsy is a clinical condition characterized mainly by excessive sleepiness and cataplexy. Hypnagogic hallucinations and sleep paralysis complete the narcoleptic tetrad; disrupted night sleep, automatic behaviors and weight gain are also usual complaints. Different studies focus on autonomic changes or dysfunctions among narcoleptic patients, such as pupillary abnormalities, fainting spells, erectile dysfunction, night sweats, gastric problems, low body temperature, systemic hypotension, dry mouth, heart palpitations, headache and extremities dysthermia. Even if many studies lack sufficient standardization or their results have not been replicated, a non-secondary involvement of the autonomic nervous system in narcolepsy is strongly suggested, mainly by metabolic and cardiovascular findings. Furthermore, the recent discovery of a high risk for overweight and for metabolic syndrome in narcoleptic patients represents an important warning for clinicians in order to monitor and follow them up for their autonomic functions. We review here studies on autonomic functions and clinical disturbances in narcoleptic patients, trying to shed light on the possible contribute of alterations of the hypocretin system in autonomic pathophysiology.es
dc.identifier.citationSleep Medicine Reviews, 2011, 15:187e196es
dc.identifier.urihttp://dx.doi.org/10.1016/j.smrv.2010.05.002es
dc.identifier.urihttp://hdl.handle.net/11447/4604
dc.language.isoenes
dc.subjectNarcolepsyes
dc.subjectCataplexyes
dc.subjectAutonomic nervous systemes
dc.subjectOrexines
dc.subjectHypocretines
dc.subjectSympathetices
dc.subjectParasympathetices
dc.titleAutonomic disturbances in narcolepsyes
dc.typeArticlees

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Autonomic disturbances in narcolepsy.pdf
Size:
358.92 KB
Format:
Adobe Portable Document Format
Description:
Texto completo
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services