Norovirus: Facts and Reflections from Past, Present, and Future

dc.contributor.authorLucero, Yalda
dc.contributor.authorMatson, David O.
dc.contributor.authorAshkenazi, Shai
dc.contributor.authorGeorge, Sergio
dc.contributor.authorO'Ryan, Miguel
dc.date.accessioned2022-05-09T17:33:58Z
dc.date.available2022-05-09T17:33:58Z
dc.date.issued2021
dc.description.abstractHuman Norovirus is currently the main viral cause of acute gastroenteritis (AGEs) in most countries worldwide. Nearly 50 years after the discovery of the "Norwalk virus" by Kapikian and colleagues, the scientific and medical community continue to generate new knowledge on the full biological and disease spectrum of Norovirus infection. Nevertheless, several areas remain incompletely understood due to the serious constraints to effectively replicate and propagate the virus. Here, we present a narrated historic perspective and summarize our current knowledge, including insights and reflections on current points of interest for a broad medical community, including clinical and molecular epidemiology, viral-host-microbiota interactions, antivirals, and vaccine prototypes. We also include a reflection on the present and future impacts of the COVID-19 pandemic on Norovirus infection and disease.es
dc.description.versionVersión Publicadaes
dc.identifier.citationLucero Y, Matson DO, Ashkenazi S, George S, O'Ryan M. Norovirus: Facts and Reflections from Past, Present, and Future. Viruses. 2021 Nov 30;13(12):2399. doi: 10.3390/v13122399. PMID: 34960668; PMCID: PMC8707792.es
dc.identifier.urihttps://doi.org/10.3390/v13122399es
dc.identifier.urihttp://hdl.handle.net/11447/6070
dc.language.isoenes
dc.subjectNoroviruses
dc.subjectEpidemiologyes
dc.subjectPreventiones
dc.subjectVaccinees
dc.titleNorovirus: Facts and Reflections from Past, Present, and Futurees
dc.typeArticlees
dcterms.sourceViruseses

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