The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science
Date
2021
Type:
Article
item.page.extent
item.page.accessRights
item.contributor.advisor
ORCID:
Journal Title
Journal ISSN
Volume Title
Publisher
item.page.isbn
item.page.issn
item.page.issne
item.page.doiurl
item.page.other
item.page.references
Abstract
Dementia is becoming increasingly prevalent in Latin America, contrasting with stable
or declining rates in North America and Europe. This scenario places unprecedented
clinical, social, and economic burden upon patients, families, and health systems. The
challenges prove particularly pressing for conditions with highly specific diagnostic
and management demands, such as frontotemporal dementia. Here we introduce
a research and networking initiative designed to tackle these ensuing hurdles, the
Multi-partner consortium to expand dementia research in Latin America (ReDLat). First,
we present ReDLat’s regional research framework, aimed at identifying the unique
genetic, social, and economic factors driving the presentation of frontotemporal dementia
and Alzheimer’s disease in Latin America relative to the US. We describe ongoing
ReDLat studies in various fields and ongoing research extensions. Then, we introduce
actions coordinated by ReDLat and the Latin America and Caribbean Consortium
on Dementia (LAC-CD) to develop culturally appropriate diagnostic tools, regional
visibility and capacity building, diplomatic coordination in local priority areas, and a
knowledge-to-action framework toward a regional action plan. Together, these research
and networking initiatives will help to establish strong cross-national bonds, support the
implementation of regional dementia plans, enhance health systems’ infrastructure, and
increase translational research collaborations across the continent.
Description
item.page.coverage.spatial
item.page.sponsorship
Citation
Frontiers in Neurology, 2021, vol.12:631722.
Keywords
Dementia, Fronto-temporal dementia, SES, SDOH, Genetics, Alzheimer’s disease, Implementation science, Latin America