Obesity and cardio-metabolic risk factors among children and adolescents with cerebral palsy

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dc.contributor.authorSalesa, Barja
dc.contributor.authorLe Roy, Catalina
dc.contributor.authorSepúlveda, Cecilia
dc.contributor.authorGuzmán, María Luisa
dc.contributor.authorOlivarez, Marithza
dc.contributor.authorFigueroa, María José
dc.date.accessioned2021-08-20T14:16:36Z
dc.date.available2021-08-20T14:16:36Z
dc.date.issued2020
dc.description.abstractBackground: obesity and associated cardiometabolic complications are increasing among adults with cerebral palsy (CP). Information in children is scarce, and there is no consensus definition of obesity. Objectives: to describe the frequency of obesity and metabolic complications in children and adolescents with CP. Methods: a descriptive, cross-sectional study performed in two outpatient pediatric special needs centers. Demographic, anthropometric (Brooks 2011), and motor function (GMFCS) data, as well as antiepileptic use, were recorded. Fasting triglycerides (TG), total cholesterol (TC), vitamin D (25OHD), glycemia (GLY), and insulinemia levels were measured. The HOMA index was calculated. Results: sixty-five patients were enrolled. Age was 10.8 ± 4.9 years; 63.1 % were male; 81.6 % had GMFCS IV-V; 43.5 % had a gastrostomy; and 83.1 % were on antiepileptics. According to their BMI, 15.4 % were underweight (< 10th percentile) and 10.8 % overweight (> 75th percentile). Overall, 6.1 % had TC ≥ 200 mg/dL, 21.4 % had TG ≥ 110 or 130 mg/dL, 4.6 % had GLY ≥ 100 mg/dL, 16.9 % had HOMA ≥ 3, and 76.9 % had 25OHD < 30 ng/mL. Children with BMI ≥ 75th percentile had higher HOMA and insulin resistance rates than those with BMI < 75th percentile. Elevated TG were associated with high motor impairment and low vitamin D. HOMA was associated to female gender and BMI ≥ 75th percentile. Conclusions: the frequency of cardiometabolic risk factors was high in this sample of pediatric patients with CP, associated with overweight, low mobility, and vitamin D deficiency. We propose a BMI > 75th percentile as cutoff point for metabolic risk factors.es
dc.identifier.citationNutrición Hospitalaria, 2020, vol.37(4):685-691es
dc.identifier.urihttp://dx.doi.org/10.20960/nh.03009es
dc.identifier.urihttp://hdl.handle.net/11447/4385
dc.language.isoenes
dc.subjectCerebral palsyes
dc.subjectObesityes
dc.subjectPediatricses
dc.subjectCardiovascular riskes
dc.subjectDyslipidemiaes
dc.subjectInsulin resistancees
dc.titleObesity and cardio-metabolic risk factors among children and adolescents with cerebral palsyes
dc.title.alternativeObesidad y factores de riesgo cardiometabólico en niños y adolescentes con parálisis cerebrales
dc.typeArticlees

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