Variability in care for children with severe acute asthma in Latin America

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dc.contributor.authorMonteverde-Fernandez, Nicolas
dc.contributor.authorDiaz, Franco
dc.contributor.authorVásquez-Hoyos, Pablo
dc.contributor.authorRotta, Alexandre T.
dc.contributor.authorGonzález-Dambrauskas, Sebastián
dc.contributor.authorLARed Network
dc.date.accessioned2021-08-06T20:46:56Z
dc.date.available2021-08-06T20:46:56Z
dc.date.issued2021
dc.description.abstractBackground: Care variability for children with severe acute asthma has been well documented in high-income countries, yet data from low- and middle-income regions are lacking. We sought to characterize the magnitude of practice variability in the care of Latin American children to identify opportunities for standardization of care. Methods: A cross-sectional study performed through a retrospective analysis of contemporaneously collected data of children with severe acute asthma admitted to a center contributing to the LARed Network registry between May 2017 and May 2019. Centers were grouped by geographic location: Atlantic (AT), South Pacific (SP), and North Central (NC). Results: Among 434 children, most received care in hospitals in the AT group (54% [235/434]), followed by the NC (23% [101/434]) and SP (23% [98/434]) groups. The majority of children in the AT (92% [215/235]) and SP (91% [89/98]) groups received nebulized salbutamol/albuterol, while metered-dose inhalers were preferred in the NC group (72% [73/101]). There was a wide variation in the use of antibiotics: AT (57% [135/235]), SP (48% [47/98]), and NC (14% [14/101]). The same was true for ipratropium bromide: AT (67% [157/235]), SP (90% [88/98]), and NC (17% [17/101]), and aminophylline: AT (57% [135/235]), NC (5% [5/101]), and SP (0% [0/98]). High-flow nasal cannula was the preferred respiratory support modality in the AT (60% [141/235]) and NC (40% [40/101]) groups, while bilevel positive airway pressure (BiPAP) use was more common in the SP group (80% [78/98]). Conclusion: We identified significant variability in care for severe acute asthma. Our findings will help to inform the design of future studies, quality improvement initiatives, and development of practice guidelines within Latin America.es
dc.identifier.citationPediatric Pulmonology, 2021 Feb, vol.56(2):384-391es
dc.identifier.urihttps://doi.org/10.1002/ppul.25212es
dc.identifier.urihttp://hdl.handle.net/11447/4256
dc.language.isoenes
dc.subjectAsthmaes
dc.subjectAsthma acute exacerbationes
dc.subjectChildrenes
dc.subjectSevere acute asthmaes
dc.subjectStatus asthmaticuses
dc.titleVariability in care for children with severe acute asthma in Latin Americaes
dc.typeArticlees

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