Macrodissection prior to closed system RT-qPCR is not necessary for estrogen receptor and HER2 concordance with IHC/FISH in breast cancer
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Abstract
An on-demand, closed RT-qPCR, the GeneXpert (GX) system, has the potential to provide biomarker information in low-resourced settings and elsewhere. We used this system with a research use only versio...
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Biomarkers, Tumor / genetics , Biomarkers, Tumor / metabolism , Breast Neoplasms / genetics* , Carcinoma, Intraductal, Noninfiltrating / diagnosis , Gene Expression Regulation, Neoplastic , Immunohistochemistry / methods* , Pathology, Clinical / methods , Receptor, ErbB-2 / genetics* , Receptors, Estrogen / metabolism , Receptor, ErbB-2 / metabolism
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