Life-threatening complications following orthognathic surgery in a patient with undiagnosed hereditary angioedema

Simple item page
dc.contributor.authorCifuentes, Julio
dc.contributor.authorPalisson, Francis
dc.contributor.authorValladares, Salvador
dc.contributor.authorJerez, Daniel
dc.date.accessioned2017-04-17T13:37:53Z
dc.date.available2017-04-17T13:37:53Z
dc.date.issued2013
dc.description.abstractAs described in the literature, hereditary angioedema (HAE) is an autosomal dominant disease that presents with recurrent events of angioedema caused by a) deficiency or b) functional alteration of the plasma protein C1 inhibitor (C1-inh); this enzyme is involved in the regulation of the complement, kallikrein-kinin, fibrinolytic, and coagulation systems. HAE is characterized by episodes of edema in the larynx, facial structures and tissues, gastrointestinal tract, or extremities. Laryngeal edema has been reported to occur predominantly after oral surgery. We describe the case of an 18-year-old Asiatic male, reporting an unremarkable medical history, who experienced complications following orthognathic surgery. Thirty hours post-op, the patient developed severe facial, pharyngeal, and glottic edema that compromised the airway, and an emergency tracheal intubation was performed. He was tested for C1-inh plasma levels, showing a sub-normal concentration and indicating a diagnosis of HAE. The patient received fresh-frozen plasma and improved throughout the day as his condition stabilized. Several cases of HAE following oral surgery have been reported, but, to the authors' knowledge, this is the first case reported following orthognathic surgery. This patient's treatment will be described, and a literature review of the disease and management methods will be provided.
dc.format.extent4
dc.identifier.citationJ Oral Maxillofac Surg. 2013 Apr;71(4):e185-188
dc.identifier.urihttp://hdl.handle.net/11447/1152
dc.identifier.urihttp://dx.doi.org/10.1016/j.joms.2012.11.023
dc.language.isoen_US
dc.publisherElsevier
dc.subjectAirway Obstruction/etiology
dc.subjectHereditary Angioedema Types I and II/complications
dc.subjectOsteotomy, Le Fort
dc.subjectOsteotomy, Sagittal Split Ramus
dc.subjectPostoperative Complications
dc.titleLife-threatening complications following orthognathic surgery in a patient with undiagnosed hereditary angioedema
dc.typeArtículo

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Life-Threatening Complications Following Orthognathic Surgery in a Patient With Undiagnosed Hereditary Angioedema.pdf
Size:
386.48 KB
Format:
Adobe Portable Document Format
Description:
Texto completo restringido
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services