Is there a risk of filarial infection during long-term missions in Haiti?

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dc.contributor.authorWeitzel, Thomas
dc.contributor.authorRosas, Reinaldo
dc.contributor.authorFica, Alberto
dc.contributor.authorDabanch, Jeannette
dc.contributor.authorPolanco, Myriam
dc.contributor.authorEgaƱa, Alicia
dc.contributor.authorTriantafilo, Vjera
dc.contributor.authorPfarr, Kenneth
dc.contributor.authorHoerauf, Achim
dc.contributor.authorReiter-Owona, Ingrid
dc.date.accessioned2017-05-15T15:06:19Z
dc.date.available2017-05-15T15:06:19Z
dc.date.issued2016
dc.description.abstractBACKGROUND: Haiti has the highest prevalence of lymphatic filariasis (Wuchereria bancrofti) in the Western Hemisphere. Still, the risk of filarial infection for long-term visitors such as humanitarian aid workers or military personnel is uncertain. The presented study analyzed the exposure to W. bancrofti in Chilean participants of the UN Stabilization Mission in Haiti (MINUSTAH) in 2011. METHODS: Blood samples collected from 531 participants were screened for antifilarial antibodies by IgG ELISA, and, if positive, analyzed by immunofluorescence assay (IFA), IgG4 ELISA, Real-Time PCR, and circulating filarial antigen (CFA) card test. RESULTS: ELISA screening was positive in 10 cases. Seroconversion occurred in only two cases (0.38%) based on ELISA values determined in samples taken before and after deployment. Positive IgG ELISA values could not be confirmed by IFA and IgG4 ELISA. Real-Time PCR and CFA testing did not reveal the presence of filaria. CONCLUSIONS: Our data indicate that in the examined cohort of MINUSTAH participants in 2011, the risk of filarial exposure or infection was low.
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dc.identifier.citationWeitzel T, Rosas R, Fica A, Dabanch J, Polanco M, EgaƱa A, Triantafilo V, Pfarr K, Hoerauf A, Reiter-Owona I. Is there a risk of filarial infection during long-term missions in Haiti? Travel Med Infect Dis. 2016 Mar-Apr;14(2):137-42.
dc.identifier.urihttp://hdl.handle.net/11447/1245
dc.identifier.urihttp://dx.doi.org/10.1016/j.tmaid.2015.12.001
dc.language.isoen_US
dc.publisherElsevier
dc.subjectHaiti
dc.subjectLong-term mission
dc.subjectLymphatic filariasis
dc.subjectWuchereria bancrofti
dc.titleIs there a risk of filarial infection during long-term missions in Haiti?
dc.typeArtĆ­culo

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