Actividad espontánea de nociceptores cutáneos en pacientes con neuropatía de fibras delgadas

dc.contributor.authorCampero, Mario
dc.contributor.authorCampero, Sebastián
dc.date.accessioned2021-10-02T22:30:12Z
dc.date.available2021-10-02T22:30:12Z
dc.date.issued2012
dc.description.abstractPainful polyneuropathy may result from selective impairment of small diameter nerve fibers, while tactile and motor functions are preserved. In these patients clinical and electrophysiological assessment is usually unrevealing. We report three patients with a pure painful polyneuropathy. One of them had neurogenic pruritus additionally. Quantitative sensory analysis disclosed a slight warm hypoesthesia (3/3) and paradoxical hot sensation (2/3) in the feet. Intraneural recordings from the peroneal nerve demonstrated abnormal spontaneous activity in 8 of 17 nociceptive afferents. One of them displayed double firing reflecting impulse multiplication. These results support the notion that patients with pain or pruritus with a distal distribution similar to a polyneuropathy, could have small diameter afferent fiber damage, despite normal function of large diameter fibers.es
dc.identifier.citationRevista Medica de Chile, 2012; 140: 1383-1390es
dc.identifier.urihttp://dx.doi.org/10.4067/S0034-98872012001100002es
dc.identifier.urihttp://hdl.handle.net/11447/4764
dc.language.isoeses
dc.subjectEctopic activityes
dc.subjectNeuralgiaes
dc.subjectNociceptorses
dc.subjectPolyneuropatieses
dc.titleActividad espontánea de nociceptores cutáneos en pacientes con neuropatía de fibras delgadases
dc.title.alternativeSpontaneous activity of cutaneous nociceptors in patients with painful polyneuropathy. report of three patientses
dc.typeArticlees

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