Infratentorial intracerebral hemorrhage. Relation of location to outcome

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dc.contributor.authorChen, Ruiqi
dc.contributor.authorWang, Xia
dc.contributor.authorAnderson, Craig
dc.contributor.authorRobinson, Thompson
dc.contributor.authorLavados, Pablo
dc.contributor.authorLindley, Richard
dc.contributor.authorChalmers, John
dc.contributor.authorDelcourt, Candice
dc.date.accessioned2020-09-04T16:15:42Z
dc.date.available2020-09-04T16:15:42Z
dc.date.issued2019-05
dc.description.abstractBackground and Purpose- Infratentorial intracerebral hemorrhage (ICH) has a poor outcome but is rarely analyzed by cerebellar versus brain stem location. We evaluated this relationship and clinical outcomes among participants of the INTERACT 1 and 2 (Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials). Methods- Participants with brain stem and cerebellar ICH were compared. Logistic regression models were used to compare outcomes of death or major disability and quality of life. Results- Of 195 included patients, 92 (47%) and 103 (53%) had brain stem and cerebellar ICH, respectively. Patients with brain stem ICH were younger (mean [SD] age, 59±13 versus 70±11 years), less female (28.3% versus 50.5%), with higher admission National Institutes of Health Stroke Scale scores (median [interquartile range], 6 [4-10) versus 3 [2-8]), less prior ICH (3% versus 17%), smaller ICH volumes (1.6 mL [1.0-2.8 mL] versus 5.1 mL [2.6-10.7 mL]), and less intraventricular extension (3% versus 39%) than those with cerebellar ICH. Brain stem ICH had higher mortality (odds ratio, 37.1; 95% CI, 1.99-692.27) and worse scores in the European Quality of Life Scale (EQ-5D) pain domain (odds ratio, 3.36; 95% CI, 1.38-8.20). Conclusions- Cerebellar and brain stem ICH differ in their clinical characteristics and prognosis, with the latter being associated with higher case fatality and worse EQ-5D scores in the pain domaines
dc.identifier.citationChen R, Wang X, Anderson CS, et al. Infratentorial Intracerebral Hemorrhage. Stroke. 2019;50(5):1257-1259. doi:10.1161/STROKEAHA.118.023766es
dc.identifier.urihttps://doi.org/10.1161/STROKEAHA.118.023766es
dc.identifier.urihttp://hdl.handle.net/11447/3398
dc.language.isoenes
dc.publisherAmerican Heart Associationes
dc.subjectBrain stemes
dc.subjectCerebellumes
dc.subjectCerebral hemorrhagees
dc.titleInfratentorial intracerebral hemorrhage. Relation of location to outcomees
dc.typeArticlees

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