Vigabatrin-induced MRI changes associated with extrapyramidal symptoms in a child with infantile spasms

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dc.contributor.authorSchonstedt, Valeria
dc.contributor.authorStecher, Ximena
dc.contributor.authorVenegas, Viviana
dc.contributor.authorSilva, Claudio
dc.date.accessioned2017-05-05T15:34:39Z
dc.date.available2017-05-05T15:34:39Z
dc.date.issued2015
dc.description.abstractVigabatrin is an antiepileptic drug used for treatment of infantile spasms. We present a female patient with infantile spasms in treatment with vigabatrin who developed ataxic movements. MRI demonstrated a symmetrical pattern of thalamic and globi pallidi diffusion restriction. While these image features have been widely described to be related to the use of vigabatrin, this case highlights the development of movement disorders in association with MRI signal changes. Awareness of the reversible nature of this condition is reassuring for the treating team and avoids unjustified studies.
dc.format.extent4
dc.identifier.citationSchonstedt V, Stecher X, Venegas V, Silva C. Vigabatrin-induced MRI changes associated with extrapyramidal symptoms in a child with infantile spasms. Neuroradiol J. 2015 Oct;28(5):515-8
dc.identifier.urihttp://hdl.handle.net/11447/1197
dc.identifier.urihttp://dx.doi.org/10.1177/1971400915598082
dc.language.isoen_US
dc.publisherSage Publications
dc.subjectVigabatrin
dc.subjectinfantile spasms
dc.subjectataxic movements
dc.subjectmagnetic resonance imaging
dc.titleVigabatrin-induced MRI changes associated with extrapyramidal symptoms in a child with infantile spasms
dc.typeArtículo

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