Impact of neonatal morbidity on the risk of developmental delay in late preterm infants

dc.contributor.authorMartínez-Nadal, Silvia
dc.contributor.authorDemestre, Xavier
dc.contributor.authorSchonhaut, Luisa
dc.contributor.authorMuñoz, Sergio R.
dc.contributor.authorSala, Pere
dc.date.accessioned2022-05-30T16:49:37Z
dc.date.available2022-05-30T16:49:37Z
dc.date.issued2018
dc.description.abstractBackground: Late preterm infants (LPI) have a higher risk of developmental delay (DD) than term-born infants. The association of perinatal complications with specific morbidity is not clear. Aim: (1) To compare the risk of DD at 4years of age between LPI who have presence or absence of any morbidity associated with the prematurity at birth, called complicated (cLPI) or uncomplicated (uLPI), and term-born infants, (2) to determine maternal and perinatal factors associated with risk of DD, and (3) to analyze, in LPI, the association between perinatal morbidity and risk of DD. Methods: A retrospective cohort study including 163 LPI - 47 cLPI and 116 uLPI - and 158 term-born infants (Terms) was conducted. Parents completed the Ages & Stages Questionnaires®3rd Spanish version (ASQ3). Risk of DD was defined as the presence of any ASQ3 domain scoring below the mean minus 2 SD. Association between risk of DD and maternal and perinatal factors was analysed using a multivariate logistic model. Incidence of risk of DD was analysed according to specific morbidity. Results: Compared to Terms, cLPI have a higher risk of DD in the communication domain. Respiratory pathology was associated with a higher risk in the communication domain. Caesarean delivery was the only maternal perinatal risk factor for DD, especially in gross motor domain. Conclusions: At the age of 4years cLPI, especially those with respiratory morbidity, had a higher risk of communication delay. Caesarean delivery was the only perinatal risk factor associated with risk of DD.es
dc.description.versionVersión Publicadaes
dc.identifier.citationMartínez-Nadal S, Demestre X, Schonhaut L, Muñoz SR, Sala P. Impact of neonatal morbidity on the risk of developmental delay in late preterm infants. Early Hum Dev. 2018 Jan;116:40-46. doi: 10.1016/j.earlhumdev.2017.11.001.es
dc.identifier.urihttps://doi.org/10.1016/j.earlhumdev.2017.11.001es
dc.identifier.urihttp://hdl.handle.net/11447/6156
dc.language.isoenes
dc.subjectAges and stages questionnaireses
dc.subjectDevelopmental delayes
dc.subjectFollow-upes
dc.subjectLate pretermes
dc.subjectNeonatal morbidityes
dc.subjectPreschoolerses
dc.titleImpact of neonatal morbidity on the risk of developmental delay in late preterm infantses
dc.typeArticlees
dcterms.sourceEarly Human Developmentes

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