Sonotrombolisis en el ataque cerebrovascular isquémico: once años de experiencia en Clínica Alemana de Santiago

Simple item page
dc.contributor.authorBrunser, Alejandro
dc.contributor.authorHoppe, Arnold
dc.contributor.authorMuñoz, Paula
dc.contributor.authorCárcamo, Daniel
dc.contributor.authorLavados, Pablo
dc.contributor.authorGaete, Javier
dc.contributor.authorRoldán, Andrés
dc.contributor.authorRivas, Rodrigo
dc.date.accessioned2017-03-02T16:00:18Z
dc.date.available2017-03-02T16:00:18Z
dc.date.issued2014
dc.description.abstractBackground: Sonothrombolysis (ST) is an emerging modality for the treatment of stroke. Aim: To assess the feasibility to perform ST in a Chilean hospital. Material and Methods: Patients attended at a private clinic with an acute ischemic stroke, between September 2002 and May 2013 and eligible for endovenous thrombolysis, were studied with a transcranial Doppler (Spencer PMD 100 or 150®). Those with an adequate sonographic window and a demonstrated arterial occlusion were monitored continuously with transcranial Doppler at the site of worst residual flow following the CLOTBUST study protocol. Results: One thousand twenty six patients were studied, of whom 136 received intravenous thrombolysis (rt-PA) and 61, aged 66 ± 18 years (59% males), were subjected to ST (7% of total). Their median National Institutes of Health Stroke Scale score was 14, the lapse from symptom onset to rt-PA was 127 minutes (43-223). Middle cerebral artery (MCA) occlusion was found in 88.5% of patients. Complete recanalization was achieved in 44.3% of patients. Sixty percent had Modified Rankin Scale of 0 to 2 at 3 months (95% confidence intervals (CI) 48.1 to 72). Case fatality was 9.8% and asymptomatic intracranial hemorrhage occurred in 9.8% (95% CI: 4.3 to 20.2). Conclusions: ST can be carried out in a complex medical center and is safe.
dc.format.extent7
dc.identifier.citationRevista Médica de Chile 2014, vol.142,p.1238-1244
dc.identifier.urihttp://hdl.handle.net/11447/985
dc.identifier.urihttp://dx.doi.org/10.4067/S0034-98872014001000002
dc.language.isospa
dc.publisherSociedad Médica de Santiago
dc.subjectStroke
dc.subjectTherapy
dc.subjectDoppler
dc.subjectThrombolytic Therapy
dc.subjectUltrasonography
dc.titleSonotrombolisis en el ataque cerebrovascular isquémico: once años de experiencia en Clínica Alemana de Santiago
dc.title.alternativeSonothrombolysis for acute ischemic stroke
dc.typeArtículo

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Sonotrombolisis en el ataque.pdf
Size:
701.99 KB
Format:
Adobe Portable Document Format
Description:
Texto Completo
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services