Dissociating the functions of three left posterior superior temporal regions that contribute to speech perception and production

Simple item page
dc.contributor.authorEkert, Justyna
dc.contributor.authorGajardo-Vidal, Andrea
dc.contributor.authorLorca, Diego
dc.contributor.authorHope, Thomas
dc.contributor.authorDick, Fred
dc.contributor.authorCrinionc, Jennifer
dc.contributor.authorGreend, David
dc.contributor.authorPrice, Cathy
dc.date.accessioned2022-05-19T19:43:42Z
dc.date.available2022-05-19T19:43:42Z
dc.date.issued2021
dc.description.abstractPrior studies have shown that the left posterior superior temporal sulcus (pSTS) and left temporo-parietal junction (TPJ) both contribute to phonological short-term memory, speech perception and speech production. Here, by conducting a within-subjects multi-factorial fMRI study, we dissociate the response profiles of these regions and a third region - the anterior ascending terminal branch of the left superior temporal sulcus (atSTS), which lies dorsal to pSTS and ventral to TPJ. First, we show that each region was more activated by (i) 1-back matching on visually presented verbal stimuli (words or pseudowords) compared to 1-back matching on visually presented non-verbal stimuli (pictures of objects or non-objects), and (ii) overt speech production than 1-back matching, across 8 types of stimuli (visually presented words, pseudowords, objects and non-objects and aurally presented words, pseudowords, object sounds and meaningless hums). The response properties of the three regions dissociated within the auditory modality. In left TPJ, activation was higher for auditory stimuli that were non-verbal (sounds of objects or meaningless hums) compared to verbal (words and pseudowords), irrespective of task (speech production or 1-back matching). In left pSTS, activation was higher for non-semantic stimuli (pseudowords and hums) than semantic stimuli (words and object sounds) on the dorsal pSTS surface (dpSTS), irrespective of task. In left atSTS, activation was not sensitive to either semantic or verbal content. The contrasting response properties of left TPJ, dpSTS and atSTS was cross-validated in an independent sample of 59 participants, using region-by-condition interactions. We also show that each region participates in non-overlapping networks of frontal, parietal and cerebellar regions. Our results challenge previous claims about functional specialisation in the left posterior superior temporal lobe and motivate future studies to determine the timing and directionality of information flow in the brain networks involved in speech perception and production.es
dc.description.versionVersión publicadaes
dc.identifier.citationkert JO, Gajardo-Vidal A, Lorca-Puls DL, Hope TMH, Dick F, Crinion JT, Green DW, Price CJ. Dissociating the functions of three left posterior superior temporal regions that contribute to speech perception and production. Neuroimage. 2021 Dec 15;245:118764. doi: 10.1016/j.neuroimage.2021.118764es
dc.identifier.urihttps://doi.org/10.1016/j.neuroimage.2021.118764es
dc.identifier.urihttp://hdl.handle.net/11447/6107
dc.language.isoenes
dc.subjectLeft posterior superior temporal sulcuses
dc.subjectNaminges
dc.subjectReadinges
dc.subjectRepetitiones
dc.subjectfMRIes
dc.titleDissociating the functions of three left posterior superior temporal regions that contribute to speech perception and productiones
dc.typeArticlees
dcterms.sourceNeuroImagees

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Dissociating the functions of three left posterior superior temporal regions that contribute to speech perception and production.pdf
Size:
1.75 MB
Format:
Adobe Portable Document Format
Description:
Texto completo
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Ciencias de la Salud

Implementado por OpenGeek Services