A prospective randomized study comparing bipolar plasmakinetic transurethral resection of the prostate and monopolar transurethral resection of the prostate for the treatment of Benign Prostatic Hyperplasia: effi cacy, sexual function, Quality of Life, and complications

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dc.contributor.authorOtaola-Arca, Hugo
dc.contributor.authorÁlvarez-Ardura, Manuel
dc.contributor.authorFernández, Mario
dc.contributor.authorMolina-Escudero, Roberto
dc.contributor.authorPáez-Borda, Álvaro
dc.date.accessioned2021-08-31T18:11:23Z
dc.date.available2021-08-31T18:11:23Z
dc.date.issued2021
dc.description.abstractObjective: To generate high-quality data comparing the clinical effi cacy and safety profi le between monopolar transurethral resection of the prostate (M-TURP) and bipolar plasmakinetic resection of the prostate (PK-TURP) for benign prostatic hyperplasia (BPH). Materials and Methods: Prospective, randomized, single-blinded study conducted in a tertiary-care public institution (Dec/2014-Aug/2016). Inclusion criteria: prostate of <80g in patients with drug-refractory lower urinary tract symptoms (LUTS), complications derived from BPH, or both. Exclusion criteria: a history of pelvic surgery/radiotherapy, neurogenic bladder dysfunction or documented/suspected prostate carcinoma. Treatment effi cacy evaluated at 1, 3, 6 and 12 months. Effi cacy outcomes: international prostate symptom score (IPSS), quality-of-life (QoL) score, international index of erectile function-5 (IIEF-5), maximum urinary fl ow rate (Qmax), postvoid residual urine (PVRU) volume, and prostate volume (PV). Complications and sequelae also assessed. Comparisons performed with parametric/non-parametric tests. Results: Out of the 100 hundred patients, 84 qualifi ed for the analysis (45 M-TURP/39 PK-TURP). No signifi cant differences found in baseline characteristics or operative data, except for a longer operative time in PK-TURP (MD:7.9min; 95%CI:0.13-15.74; p=0.04). No differences found in IPSS, Qmax or PVRU volume. QoL score at 12 months was higher in PK-TURP (MD:0,9points; 95%CI:0.18-1.64; p=0.01). No differences in sexual function, PV, complications or sequelae were found. This study is “rigorous” (Jadadscale) and has a low risk of bias (Cochrane-Handbook). Conclusions: Based on this controlled trial, there is not signifi cant variation in effectiveness and safety between M-TURP and PK-TURP for the treatment of BPH. The small difference in QoL between PK-TURP and M-TURP at the one-year follow-up is not perceivable by the patients and, therefore, not clinically relevant.es
dc.identifier.citationInternational Brazilian Journal of Urology, 2021, vol. 47(1): 131-144es
dc.identifier.urihttps://dx.doi.org/10.1590/S1677-5538.IBJU.2019.0766es
dc.identifier.urihttp://hdl.handle.net/11447/4553
dc.language.isoenes
dc.subjectTransurethral Resection of Prostatees
dc.subjectQuality of Lifees
dc.subjectProstatic Hyperplasiaes
dc.titleA prospective randomized study comparing bipolar plasmakinetic transurethral resection of the prostate and monopolar transurethral resection of the prostate for the treatment of Benign Prostatic Hyperplasia: effi cacy, sexual function, Quality of Life, and complicationses
dc.typeArticlees

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