Effect of the nature of the nucleophile and solvent on an SNAr reaction

Simple item page
dc.contributor.authorGazitúa, Marcela
dc.contributor.authorTapia, Ricardo A.
dc.contributor.authorContreras, Renato
dc.contributor.authorCampodónico, Paola
dc.date.accessioned2022-05-24T21:53:23Z
dc.date.available2022-05-24T21:53:23Z
dc.date.issued2018
dc.description.abstractThe reaction of 2,4-dinitrobenzenesulfonyl chloride toward propylamine was kinetically evaluated in 19 organic solvents and 10 ionic liquids as reaction media. This study was compared with a previous study to experimentally show that solvent effects and the nature of the reacting pair drastically affect the reaction rate and the reaction mechanism. While the reaction of the reference electrophile 2,4-dinitrobenzenesulfonyl chloride with piperidine is favored in polar solvents with the ability to donate or accept hydrogen bonds, the reaction with propylamine is favored in solvents with the ability to accept hydrogen bonds.es
dc.description.versionVersión Publicadaes
dc.identifier.citationGazitúa, Marcela; Tapia, Ricardo A.; Contreras, Renato; Campodónico, Paola. Effect of the nature of the nucleophile and solvent on an SNAr reaction. New Journal of Chemistry, 2018, 42, 260--264es
dc.identifier.urihttps://doi.org/10.1039/c7nj03212aes
dc.identifier.urihttp://hdl.handle.net/11447/6135
dc.language.isoenes
dc.relation.projectThis work was supported by the Postdoctoral fellowships 3120060, Fondecyt grants 11140172, 1150759, project ICM-MINECON, RC-130006 – CILIS, granted by Fondo de Innovacio ́n para La Competitividad Del Ministerio de Economı ́a, Fomento y Turismo, Chile and Instituto de Ciencias e Innovacio ́n en Medicina (ICIM- CAS UDD).es
dc.titleEffect of the nature of the nucleophile and solvent on an SNAr reactiones
dc.typeArticlees
dcterms.sourceNew Journal of Chemistryes

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Effect of the nature of the nucleophile and solvent on an SNAr reaction.pdf
Size:
1.39 MB
Format:
Adobe Portable Document Format
Description:
Texto completo
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services