Case−Control Study of Risk Factors for Meningococcal Disease in Chile

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dc.contributor.authorOlea, Andrea
dc.contributor.authorMatute, Isabel
dc.contributor.authorGonzalez, Claudia
dc.contributor.authorDelgado, Iris
dc.contributor.authorPoffald, Lucy
dc.contributor.authorPedroni, Elena
dc.contributor.authorAlfaro, Tania
dc.contributor.authorHirmas, Macarena
dc.contributor.authorNájera, Manuel
dc.contributor.authorGormaz, Ana
dc.contributor.authorLopez, Dario
dc.contributor.authorSergio, Loayza
dc.contributor.authorFerreccio, Catterina
dc.contributor.authorGallegos, Doris
dc.contributor.authorFuentes, Rodrigo
dc.contributor.authorVial, Pablo
dc.contributor.authorAguilera, Ximena
dc.date.accessioned2017-09-04T18:48:07Z
dc.date.available2017-09-04T18:48:07Z
dc.date.issued2017
dc.description.abstractAn outbreak of meningococcal disease with a case-fatality rate of 30% and caused by predominantly serogroup W of Neisseria meningitidis began in Chile in 2012. This outbreak required a case−control study to assess determinants and risk factors for infection. We identified confirmed cases during January 2012−March 2013 and selected controls by random sampling of the population, matched for age and sex, resulting in 135 case-patients and 618 controls. Sociodemographic variables, habits, and previous illnesses were studied. Analyses yielded adjusted odds ratios as estimators of the probability of disease development. Results indicated that conditions of social vulnerability, such as low income and overcrowding, as well as familial history of this disease and clinical histories, especially chronic diseases and hospitalization for respiratory conditions, increased the probability of illness. Findings should contribute to direction of intersectoral public policies toward a highly vulnerable social group to enable them to improve their living conditions and health.
dc.format.extent9
dc.identifier.citationOlea A, Matute I, González C, Delgado I, Poffald L, Pedroni E, Alfaro T, Hirmas M, Nájera M, Gormaz A, López D, Loayza S, Ferreccio C, Gallegos D, Fuentes R, Vial P, Aguilera X. Case-Control Study of Risk Factors for Meningococcal Disease in Chile. Emerg Infect Dis. 2017 Jul;23(7):1070-1078.
dc.identifier.urihttp://hdl.handle.net/11447/1642
dc.identifier.urihttp://dx.doi.org/10.3201/eid2307.160129
dc.language.isoen_US
dc.publisherCenters for Disease Control and Prevention
dc.subjectmeningococcal disease
dc.subjectNeisseria meningitidis
dc.subjectSociodemographic variables
dc.subjectclinical histories
dc.subjectChile
dc.titleCase−Control Study of Risk Factors for Meningococcal Disease in Chile
dc.typeArtículo

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