Suicide HSVtk Gene Delivery by Neurotensin-Polyplex Nanoparticles via the Bloodstream and GCV Treatment Specifically Inhibit the Growth of Human MDA-MB-231 Triple Negative Breast Cancer Tumors Xenografted in Athymic Mice

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Suicide HSVtk Gene Delivery by Neurotensin-Pol.pdf (3.94 MB)

Date

2014

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Artículo

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Artículos Medicina y Ciencias de la Salud

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15

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Public Library of Science

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http://hdl.handle.net/11447/1019
 http://dx.doi.org/ 10.1371/journal.pone.0097151

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12

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Abstract

The human breast adenocarcinoma cell line MDA-MB-231 has the triple-negative breast cancer (TNBC) phenotype, which is an aggressive subtype with no specific treatment. MDA-MB-231 cells express neurote...

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Centro de Medicina Regenerativa

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Citation

PLoS One. 2014 May 13;9(5):e97151

Keywords

Animals , Cell Proliferation/drug effects , Genetic Therapy/methods , Mice , Nanoparticles/metabolism , Triple Negative Breast Neoplasms/physiopathology

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