Pemphigus-like eruption as a complication of molluscum contagiosum treatment with imiquimod in a 5-year-old girl

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Abstract

Pemphigus and pemphigus-like reactions can be triggered by a variety of medications including topical therapies, such as imiquimod. While the association between imiquimod and pemphigus-like reactions has been reported in adults, this is the first report of a generalized reaction beyond the site of imiquimod application in a child. The mechanism by which this occurs may be through a unique pathway, separate from the classic antibody-mediated pathway. Our patient had a full recovery without recurrence after cessation of the inciting drug.

Description

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Citation

Pediatric Dermatology, 2020, vol. 37(2): 379-380

Keywords

Drug reaction, Imiquimod, Pemphigus-like reaction

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