Uso de cannabis en jóvenes hospitalizados por un primer episodio de psicosis: un estudio caso-control

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dc.contributor.authorCastañeda, Carmen Paz
dc.contributor.authorIruretagoyena, Bárbara
dc.contributor.authorNachar, Rubén
dc.contributor.authorMancilla, Felipe
dc.contributor.authorDíaz, Camila
dc.contributor.authorGallardo, Carlos
dc.contributor.authorMena, Cristián
dc.contributor.authorRamírez-Mahaluf, Juan Pablo
dc.contributor.authorUndurraga, Juan
dc.contributor.authorGonzález-Valderrama, Alfonso
dc.contributor.authorCrossley, Nicolás A.
dc.date.accessioned2021-08-24T14:46:19Z
dc.date.available2021-08-24T14:46:19Z
dc.date.issued2020
dc.description.abstractBackground: Cannabis use among young people in Chile has increased significantly in the last years. There is a consistent link between cannabis and psychosis. Aim: To compare cannabis use in patients with a first episode of psychosis and healthy controls. Material and Methods: We included 74 patients aged 20 ± 3 years (78% males) admitted to hospital with a first episode of psychosis and a group of 60 healthy controls aged 23 ± 4 years (63% males). Cannabis consumption was assessed, including age of first time use and length of regular use. Results: Patients with psychosis reported a non-significantly higher frequency of life-time cannabis use. Patients had longer periods of regular cannabis use compared with healthy subjects (Odds ratio [OR] 2.4; 95% confi-dence intervals [CI] 1.14-5.05). Patients also used cannabis for the first time at an earlier age (16 compared with 17 years, p < 0.0). The population attributable fraction for regular cannabis use associated with hospital admissions due to psychosis was 17.7% (95% CI 1.2-45.5%). Conclusions: Cannabis use is related to psychosis in this Chilean group of patients. This relationship is stronger in patients with early exposure to the drug and longer the regular use. One of every five admissions due to psychosis is associated with cannabis consumption. These data should influence cannabis legisla-tion and the public policies currently being discussed in Chile.es
dc.format.extent8 p.es
dc.identifier.citationRevista médica de Chile 2020; 148: 1606-1613es
dc.identifier.urihttps://doi.org/10.4067/S0034-98872020001101606es
dc.identifier.urihttp://hdl.handle.net/11447/4436
dc.language.isoeses
dc.subjectCannabises
dc.subjectCase-Control Studieses
dc.subjectPsychotic Disorderses
dc.titleUso de cannabis en jóvenes hospitalizados por un primer episodio de psicosis: un estudio caso-controles
dc.title.alternativeCannabis use among hospitalized young people experiencing a first episode of psychosis: a case control studyes
dc.typeArticlees

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