Prevalence and Risk Factors of Antibodies to Anaplasma spp. in Chile: A Household-Based Cross-Sectional Study in Healthy Adults and Domestic Dogs

Simple item page
dc.contributor.authorAcosta-Jamett, Gerardo
dc.contributor.authorWeitzel, Thomas
dc.contributor.authorLópez, Javier
dc.contributor.authorAlvarado, Doris
dc.contributor.authorAbarca, Katia
dc.date.accessioned2021-08-17T18:06:32Z
dc.date.available2021-08-17T18:06:32Z
dc.date.issued2020
dc.description.abstractBackground: Pet-related tick-borne infections constitute an emerging problem in human and veterinary medicine worldwide. In Chile, two pathogens of the Anaplasmataceae family, Anaplasma platys and Ehrlichia canis, have been identified in recent years in dogs and vectors. This epidemiological survey aimed to determine the human and canine seroprevalence of Anaplasma spp. in urban and rural areas of different regions in Chile and to analyze the factors associated with seropositivity. Methods: We performed a cross-sectional household-based study in four regions, where healthy adults and their household dogs were included. Households were chosen by double stratified random sampling in urban areas and by convenience sampling in rural areas. Anaplasma seroreactivity was determined by a commercial microimmunofluorescence assay using Anaplasma phagocytophilum antigens. A questionnaire survey was applied to assess risk factors for Anaplasma seropositivity. Results: A total of 1105 persons and 905 dogs were included. The overall seroprevalence in humans was 9.4%, ranging from 5.6% in central Chile to 13.7% in the extreme north; in dogs the overall prevalence was 44.0% and ranged from 37.2% in the northern region to 61.1% in central Chile. Risk factors for human seropositivity were lower education and external deworming of dogs, whereas canine seropositivity was associated to urban site, mixed-breed, older animals, and tick infestation. Conclusions: This cross-sectional study suggests a broad exposure of both dogs and dog owners to Anaplasma or related agents in Chile. Further epidemiological and clinical studies are necessary to understand the complete spectrum and epidemiology of tick-borne zoonotic infections in the different ecoclimatic regions of Chile.es
dc.identifier.citationVector-Borne and Zoonotic Diseases, 2020, vol.XX, n° XX,es
dc.identifier.urihttps://dx.doi.org/10.1089/vbz.2019.2587es
dc.identifier.urihttp://hdl.handle.net/11447/4347
dc.language.isoenes
dc.subjectAnaplasmataceaees
dc.subjectAnaplasmaes
dc.subjectEpidemiologyes
dc.subjectSeroprevalencees
dc.subjectTick-borne infectionses
dc.subjectZoonotic diseaseses
dc.titlePrevalence and Risk Factors of Antibodies to Anaplasma spp. in Chile: A Household-Based Cross-Sectional Study in Healthy Adults and Domestic Dogses
dc.typeArticlees

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Prevalence and risk factors of antibodies to Anaplasma spp. in Chile – a household-based cross-sectional study in healthy adults and domestic dogs.pdf
Size:
268.43 KB
Format:
Adobe Portable Document Format
Description:
Texto completo
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services