Influence of Inoculum Effect on the Efficacy of Daptomycin Monotherapy and in Combination with -Lactams against Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions
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Abstract
Enterococcus faecium isolates that harbor LiaFSR substitutions but are
phenotypically susceptible to daptomycin (DAP) by current breakpoints are problem-
atic, since predisposition to resistance may...
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Citation
Citation Kebriaei R, Rice SA, Singh KV, Stamper KC, Dinh AQ, Rios R, Diaz L, Murray BE, Munita JM, Tran TT, Arias CA, Rybak MJ. 2018. Influence of inoculum effect on the efficacy of daptomycin monotherapy and in combination with β-lactams against daptomycin- susceptible Enterococcus faecium harboring LiaSR substitutions. Antimicrob Agents Chemother 62:e00315-18. https://doi.org/10 .1128/AAC.00315-18.
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