Effect-Site Target-Controlled Infusion in the Obese: Model Derivation and Performance Assessment
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Abstract
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The aim of this study is to derive a propofol pharmacokinetic (PK) pharmacodynamic (PD) model to perform effect-site target-controlled infusion (TCI) in obese patients, and to analyze it...
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Cortínez, Luis I. MD*; Sepúlveda, Pablo MD†; Rolle, Augusto MD*; Cottin, Pauline PharmD‡; Guerrini, Alexandre PhD‡; Anderson, Brian J. PhD, FANZCA§ Effect-Site Target-Controlled Infusion in the Obese: Model Derivation and Performance Assessment, Anesthesia & Analgesia: October 2018 - Volume 127 - Issue 4 - p 865-872 doi: 10.1213/ANE.0000000000002814
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