Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry

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Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry-Carvajal D.pdf (1.16 MB)

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2019-05

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Article

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Artículos Medicina y Ciencias de la Salud

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American Association for Cancer Research.

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doi:10.1158/1078-0432.CCR-18-2599
 http://hdl.handle.net/11447/3412

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Abstract

Purpose: Imaging mass cytometry (IMC) uses metal-conjugated antibodies to provide multidimensional, objective measurement of protein targets. We used this high-throughput platform to perform an 18-ple...

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Citation

Carvajal-Hausdorf DE, Patsenker J, Stanton KP, et al. Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry. Clin Cancer Res. 2019;25(10):3054-3062. doi:10.1158/1078-0432.CCR-18-2599

Keywords

HER2 , Immunohistochemistry , T-cell , Imaging mass cytometry , Multiplexing

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